Reaction profile

The FDA adverse-event record for basophilia

391 FDA reports name basophilia, a high-volume reaction in the CVM extract (VeDDRA 2219). Plate stamps and neighbourhood peers follow.

#738 of 2,481
by report volume (all reactions)
391
reports citing this reaction
26.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Basophilia has 391 reports now versus 378 in that prior snapshot: 13 more (3.4%).

Report change
+13
Death-coded reports
+2
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Basophilia changes

FDA AER · VeDDRA plate

Code 2219 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 391 reports
  • DEATH-HOT 26.1%
  • MID-PACK #738/2481
  • PHOTO-FINISH Urination related to…
  • SPECIES-DOG Dog · 304
  • DRUG-LEAD Maropitant Citrate · 42
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Urination related to convulsion (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Basophilia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Stranguria · near392Basophilia · this reaction391Urination related to… · near391Fasciculation · near390Application site sore · near389Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Basophilia

Basophilia: high death-coded share in the FDA AER plate

Signature read: 102 death-coded reports is a heavy tail count for Basophilia in the CVM extract. Report volume is upper-third scale: 391 named reports in the openFDA extract. Death-coded share is upper-third: 102 of 391 reports (26.1% of named reports). Nearest volume peer: Urination related to convulsion (±0 reports). Lead species Dog (304). Lead co-reported drug Maropitant Citrate (42).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 304
Cat 80
Horse 6
Rabbit 1

Breeds Most Affected

Domestic Shorthair 47
Retriever - Labrador 34
Shepherd Dog - German 21
Crossbred Canine/dog 19
Retriever - Golden 17
Boxer (German Boxer) 15
Chihuahua 12
Shih Tzu 12
Domestic Longhair 10
Pit Bull 10

Associated Drugs

Maropitant Citrate 42
Milbemycin Oxime + Spinosad 37
Afoxolaner 34
Carprofen 28
Gabapentin 25
Ivermectin + Pyrantel As Pamoate Salt 23
Fluralaner Chew Tablets 20
Doxycycline 19
Milbemycin Oxime + Praziquantel 19
Prednisone 18
Metronidazole 18
Oclacitinib Maleate 16
Grapiprant 16
Polysulfated Glycosaminoglycan 15
Famotidine 14
Bedinvetmab 14
Spinosad 13
Cefovecin 13
Meloxicam 12
Enrofloxacin 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Basophilia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (391 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Basophilia (#738 of 2,481 by report volume); death-coded 26.1%. PlainBreed reaction plate · death-coded report count stamp 102 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →