Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - parainfluenza

Name: Lack of efficacy (virus) - parainfluenza - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

12 FDA reports name lack of efficacy (virus) - parainfluenza, a lower-volume reaction in the CVM extract (VeDDRA 2822). Plate stamps and neighbourhood peers follow.

#2388 of 2,481
by report volume (all reactions): 12
reports citing this reaction: 16.7%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (virus) - parainfluenza has 12 reports now versus 12 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (virus) - parainfluenza changes

FDA AER · VeDDRA plate

Code 2822 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 12 reports
DEATH-ELEV 16.7%
BOTTOM-DECILE #2388/2481
PHOTO-FINISH Agitated state of mind
SPECIES-DOG Dog · 10
DRUG-LEAD Doxycycline · 5
DESK-WIDE 9 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Agitated state of mind (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - parainfluenza

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Lack of efficacy (virus) - parainfluenza

What the FDA AER plate says about Lack of efficacy (virus) - parainfluenza

Signature read: 12 reports place Lack of efficacy (virus) - parainfluenza in the lower third of FDA AER volume (#2388 of 2,481). Report volume is lower-third scale: 12 named reports in the openFDA extract. 2 of 12 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Agitated state of mind (±0 reports). Lead species Dog (10). Lead co-reported drug Doxycycline (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Doxycycline appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 10

Cattle 2

Breeds Most Affected

Cattle (other) 2

Retriever - Golden 2

Plott 2

Retriever - Labrador 1

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Bulldog - French 1

Crossbred Canine/dog 1

Mountain Dog - Bernese 1

Terrier - Boston 1

Associated Drugs

Doxycycline 5

Lotilaner 3

Maropitant Citrate 3

Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 3

Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2

Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 2

Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2

Gamithromycin 2

Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Vaccine, Modified Live Virus, Avirulent Live Culture 2

Enrofloxacin 2

Prednisone 2

Trazadone 2

Gabapentin 2

Canine Distemper,Parvovirus Vaccine 2

Moxidectin 1

Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 1

Milbemycin Oxime + Praziquantel 1

Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 1

Cefovecin 1

Oclacitinib Maleate 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (virus) - parainfluenza (#2388 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · report volume stamp 12 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →