Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - parainfluenza

11 FDA adverse-event reports reference lack of efficacy (virus) - parainfluenza (VeDDRA 2822). See the species, breeds, and drugs most associated with it below.

11
reports citing this reaction
18.2%
death-coded share
Dog
most-affected species
Doxycycline
most-associated drug
Verify with FDA CVM →
11
Total Reports
2
Deaths
18.2%
Death Rate

Species Most Affected

Dog 9
Cattle 2

Breeds Most Affected

Cattle (other) 2
Retriever - Golden 2
Plott 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Retriever - Labrador 1
Crossbred Canine/dog 1
Bulldog - French 1
Mountain Dog - Bernese 1

Associated Drugs

Doxycycline 5
Lotilaner 3
Maropitant Citrate 3
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Gamithromycin 2
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 2
Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Vaccine, Modified Live Virus, Avirulent Live Culture 2
Enrofloxacin 2
Prednisone 2
Trazadone 2
Gabapentin 2
Canine Distemper,Parvovirus Vaccine 2
Milbemycin Oxime + Praziquantel 1
Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 1
Moxidectin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 1
Oclacitinib Maleate 1
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 1

Lack of efficacy (virus) - parainfluenza Reaction Insights

11 reports name Lack of efficacy (virus) - parainfluenza; 2 recorded a death outcome (18.2% of reported events, not a population-level mortality rate). VeDDRA code: 2822.

By species: Dog (9 reports), Cattle (2 reports). By breed: Cattle (other) (2), Retriever - Golden (2), Plott (2).

Most co-reported drugs: Doxycycline (5 reports), Lotilaner (3 reports), Maropitant Citrate (3 reports), Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.