Lack of efficacy (virus) - parainfluenza

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VeDDRA Code: 2822

11 adverse event reports referencing this reaction

11
Total Reports
2
Deaths
1820.0%
Death Rate

Species Most Affected

Dog 9
Cattle 2

Breeds Most Affected

Cattle (other) 2
Retriever - Golden 2
Plott 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Retriever - Labrador 1
Crossbred Canine/dog 1
Bulldog - French 1
Mountain Dog - Bernese 1

Associated Drugs

Doxycycline 5
Lotilaner 3
Maropitant Citrate 3
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Gamithromycin 2
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 2
Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Vaccine, Modified Live Virus, Avirulent Live Culture 2
Enrofloxacin 2
Prednisone 2
Trazadone 2
Gabapentin 2
Canine Distemper,Parvovirus Vaccine 2
Milbemycin Oxime + Praziquantel 1
Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 1
Moxidectin 1
Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 1
Oclacitinib Maleate 1
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 1

Data Summary

Metric Value
Total reports referencing reaction 11
Reports with fatal outcome 2
Case-fatality rate (reported events) 1820.0%
Species observed 2
Breeds observed 8
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2822.

Lack of efficacy (virus) - parainfluenza Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 11 adverse event reports that reference Lack of efficacy (virus) - parainfluenza as a reaction term, including 2 reports with a death outcome — a 1820.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2822, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Lack of efficacy (virus) - parainfluenza appears most frequently in reports for Dog (9 reports), Cattle (2 reports) — with Dog dominating at 9 entries. Within those species, the breeds most often named alongside this reaction are Cattle (other) (2), Retriever - Golden (2), Plott (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Lack of efficacy (virus) - parainfluenza are Doxycycline (5 reports), Lotilaner (3 reports), Maropitant Citrate (3 reports), Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim (2 reports), with Doxycycline appearing alongside this reaction in 5 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial