Reaction profile

The FDA adverse-event record for hyperkalemic condition

19 FDA reports name hyperkalemic condition, a lower-volume reaction in the CVM extract (VeDDRA 1944). Plate stamps and neighbourhood peers follow.

#2184 of 2,481
by report volume (all reactions)
19
reports citing this reaction
36.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperkalemic condition has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperkalemic condition changes

FDA AER · VeDDRA plate

Code 1944 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 19 reports
  • DEATH-HOT 36.8%
  • LOWER-Q #2184/2481
  • PHOTO-FINISH Adaptor, damaged
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Milbemycin Oxime… · 5
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Hyperkalemic condition

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, damaged · near19Amaurosis (see also P… · near19Anhidrosis · near19Cholelithiasis · near19Hyperkalemic condition · thi…19Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperkalemic condition

Hyperkalemic condition: high death-coded share in the FDA AER plate

Signature read: 19 reports place Hyperkalemic condition in the lower third of FDA AER volume (#2184 of 2,481). Report volume is lower-third scale: 19 named reports in the openFDA extract. Death-coded share is upper-third: 7 of 19 reports (36.8% of named reports). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Dog (14). Lead co-reported drug Milbemycin Oxime + Spinosad (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Cat 5

Breeds Most Affected

Domestic Shorthair 3
Pug 2
Retriever - Golden 2
Shih Tzu 1
Terrier - Jack Russell 1
Retriever - Labrador 1
Poodle - Standard 1
Schnauzer - Miniature 1
Siamese 1
Terrier - West Highland White 1

Associated Drugs

Milbemycin Oxime + Spinosad 5
Grapiprant 4
Cyclosporine 3
Deracoxib 3
Robenacoxib 3
Prednisone 3
Desoxycorticosterone Pivalate 2
Fluralaner 2
Fish Oil 2
Buprenorphine 2
Isoflurane 2
Sodium Chloride + Sodium Lactate + Potassium Chloride + Calcium Chloride 2
Desoxycortone 2
Tramadol 2
Prednisolone Trimeprazine Tartrate 1
Diphenhydramine 1
Hydroxyzine 1
Antihistamine (Unknown) 1
Avocado/Soybean Unsaponifiable + Glucosamine + Sodium Chondroitin Sulfate 1
Ivermectin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperkalemic condition (#2184 of 2,481 by report volume); death-coded 36.8%. PlainBreed reaction plate · report volume stamp 19 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →