Reaction profile

The FDA adverse-event record for gingival swelling

Name: Gingival swelling - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

17 FDA reports name gingival swelling, a lower-volume reaction in the CVM extract (VeDDRA 2441). Plate stamps and neighbourhood peers follow.

#2239 of 2,481
by report volume (all reactions): 17
reports citing this reaction: 23.5%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Gingival swelling has 17 reports now versus 17 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Gingival swelling changes

FDA AER · VeDDRA plate

Code 2441 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 17 reports
DEATH-HOT 23.5%
BOTTOM-DECILE #2239/2481
PHOTO-FINISH Anoestrus
SPECIES-DOG Dog · 12
DRUG-LEAD Ivermectin(1.55%)… · 3
DESK-WIDE 14 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoestrus (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Gingival swelling

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Gingival swelling

What the FDA AER plate says about Gingival swelling

Signature read: 17 reports place Gingival swelling in the lower third of FDA AER volume (#2239 of 2,481). Report volume is lower-third scale: 17 named reports in the openFDA extract. 4 of 17 reports were death-coded (23.5% of named reports, not a population mortality rate). Nearest volume peer: Anoestrus (±0 reports). Lead species Dog (12). Lead co-reported drug Ivermectin(1.55%)/Praziquantel(7.75%) Paste (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin(1.55%)/Praziquantel(7.75%) Paste appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 12

Horse 3

Cat 2

Breeds Most Affected

Shih Tzu 3

Horse (unknown) 2

Belgian Draft, also called Brabant or Brabants trekpaard 1

Shepherd Dog - Australian 1

Retriever - Labrador 1

Terrier - Boston 1

Terrier - Bull - Staffordshire 1

Domestic Longhair 1

Rottweiler 1

Chihuahua 1

Associated Drugs

Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3

Cyclosporine 3

Carprofen 3

Fluralaner Chew Tablets 1

Doxycycline Hyclate 1

Trilostane 1

Ketoconazole 1

Cefovecin 1

Afoxolaner 1

Ivermectin 1

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1

Milbemycin Oxime + Lufenuron + Praziquantel 1

Oclacitinib Maleate 1

Pimobendan 1

Moxidectin 1

Sarolaner 1

Benadryl 1

Ketoconazole Shampoo 1

Immunotherapy 1

Prescription Diet 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Gingival swelling (#2239 of 2,481 by report volume); death-coded 23.5%. PlainBreed reaction plate · report volume stamp 17 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →