PR-PERITONEAL EFFUSION

Verify with FDA CVM →

VeDDRA Code: 99663

65 adverse event reports referencing this reaction

65
Total Reports
59
Deaths
9080.0%
Death Rate

Species Most Affected

Dog 46
Cat 16
Cattle 2
Pig 1

Breeds Most Affected

Domestic (unspecified) 11
Retriever - Labrador 11
Crossbred Canine/dog 9
Domestic Shorthair 3
Spaniel - Cocker American 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Pug 2
Schnauzer (unspecified) 2
Chow Chow 2
Retriever - Golden 2

Associated Drugs

Deracoxib 12
Meloxicam 10
Cefovecin Sodium 7
Carprofen 6
Firocoxib 3
Maropitant 3
Dexmedetomidine Hydrochloride 3
Amoxicillin, Clavulanate 2
Spinosad 2
Propofol 2
Cefovecin 2
Grapiprant 2
Selamectin 1
Milbemycin 1
Melarsomine Dihydrochloride 1
Ivermectin, Pyrantel 1
Oxytetracycline, Flunixin Meglumine 1
Lufenuron 1
Atipamezole 1
Moxidectin 1

Data Summary

Metric Value
Total reports referencing reaction 65
Reports with fatal outcome 59
Case-fatality rate (reported events) 9080.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99663.

PR-PERITONEAL EFFUSION Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 65 adverse event reports that reference PR-PERITONEAL EFFUSION as a reaction term, including 59 reports with a death outcome — a 9080.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99663, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

PR-PERITONEAL EFFUSION appears most frequently in reports for Dog (46 reports), Cat (16 reports), Cattle (2 reports) — with Dog dominating at 46 entries. Within those species, the breeds most often named alongside this reaction are Domestic (unspecified) (11), Retriever - Labrador (11), Crossbred Canine/dog (9). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with PR-PERITONEAL EFFUSION are Deracoxib (12 reports), Meloxicam (10 reports), Cefovecin Sodium (7 reports), Carprofen (6 reports), with Deracoxib appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial