Reaction profile

The FDA adverse-event record for unable to rise

1,488 FDA reports name unable to rise, a high-volume reaction in the CVM extract (VeDDRA 2045). Plate stamps and neighbourhood peers follow.

#286 of 2,481
by report volume (all reactions)
1,488
reports citing this reaction
37.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unable to rise has 1,488 reports now versus 1,458 in that prior snapshot: 30 more (2.1%).

Report change
+30
Death-coded reports
+10
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unable to rise changes

FDA AER · VeDDRA plate

Code 2045 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,488 reports
  • DEATH-HOT 37.6%
  • UPPER-Q #286/2481
  • PHOTO-FINISH Bacterial skin infect…
  • SPECIES-DOG Dog · 1,269
  • DRUG-LEAD Bedinvetmab · 256
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bacterial skin infection NOS (±4 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Unable to rise

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Gait abnormality · near1512Unable to rise · this reacti…1488Bacterial skin infect… · near1484Unable to walk · near1484Vestibular disorder N… · near1471Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Unable to rise

Unable to rise: high death-coded share in the FDA AER plate

Signature read: 560 death-coded reports is a heavy tail count for Unable to rise in the CVM extract. Report volume is upper-third scale: 1,488 named reports in the openFDA extract. Death-coded share is upper-third: 560 of 1,488 reports (37.6% of named reports). Nearest volume peer: Bacterial skin infection NOS (±4 reports). Lead species Dog (1,269). Lead co-reported drug Bedinvetmab (256).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,269
Cat 119
Cattle 53
Horse 26
Pig 11
Goat 3
Turkey 3
Sheep 2
Chicken 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 205
Crossbred Canine/dog 96
Retriever - Golden 81
Shepherd Dog - German 76
Domestic Shorthair 74
Boxer (German Boxer) 42
Chihuahua 36
Dog (unknown) 35
Terrier - Yorkshire 28
Shepherd Dog - Australian 27

Associated Drugs

Bedinvetmab 256
Carprofen 171
Milbemycin Oxime + Spinosad 148
Gabapentin 123
Afoxolaner 80
Spinosad 72
Maropitant Citrate 67
Trilostane 63
Moxidectin 63
Fluralaner Chew Tablets 59
Oclacitinib Maleate 55
Grapiprant 53
Prednisone 49
Tramadol 44
Ivermectin + Pyrantel As Pamoate Salt 44
Sarolaner 43
Polysulfated Glycosaminoglycan 40
Milbemycin Oxime + Praziquantel 38
Pyrantel Pamoate;Sarolaner 38
Cefovecin 34

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Unable to rise, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,488 here).

Similar death-coded share

Nearest other reactions by death-coded share (37.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unable to rise (#286 of 2,481 by report volume); death-coded 37.6%. PlainBreed reaction plate · death-coded report count stamp 560 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →