Reaction profile

The FDA adverse-event record for myelopathy nos

140 FDA adverse-event reports reference myelopathy nos (VeDDRA 2173). See the species, breeds, and drugs most associated with it below.

140
reports citing this reaction
27.9%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
140
Total Reports
39
Deaths
27.9%
Death Rate

Species Most Affected

Dog 135
Cat 4
Tiger 1

Breeds Most Affected

Retriever - Labrador 17
Shepherd Dog - German 16
Crossbred Canine/dog 10
Boxer (German Boxer) 8
Terrier - Bull - American Pit 8
Retriever - Golden 6
Chihuahua 5
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 4
Deutsche Dogge, Great Dane 3
Schnauzer - Miniature 3

Associated Drugs

Bedinvetmab 64
Carprofen 25
Gabapentin 25
Afoxolaner 11
Grapiprant 9
Oclacitinib Maleate 8
Fluralaner Chew Tablets 8
Prednisone 8
Fluralaner 13.64% 12-Week Chew 8
Trilostane 7
Dasuquin 7
Meloxicam 6
Galliprant 6
Melarsomine Dihydrochloride 5
Maropitant Citrate 5
Fluralaner 5
Unspecified Gabapentin 5
Milbemycin Oxime + Spinosad 4
Doxycycline 4
Milbemycin Oxime + Praziquantel 4

Myelopathy NOS Reaction Insights

140 reports name Myelopathy NOS; 39 recorded a death outcome (27.9% of reported events, not a population-level mortality rate). VeDDRA code: 2173.

By species: Dog (135 reports), Cat (4 reports), Tiger (1 reports). By breed: Retriever - Labrador (17), Shepherd Dog - German (16), Crossbred Canine/dog (10).

Most co-reported drugs: Bedinvetmab (64 reports), Carprofen (25 reports), Gabapentin (25 reports), Afoxolaner (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.