Reaction profile

The FDA adverse-event record for circumstance or info capable of leading to medication error

214 FDA adverse-event reports reference circumstance or info capable of leading to medication error (VeDDRA 99810). See the species, breeds, and drugs most associated with it below.

214
reports citing this reaction
1.4%
death-coded share
Unknown
most-affected species
Nitenpyram
most-associated drug
Verify with FDA CVM →
214
Total Reports
3
Deaths
1.4%
Death Rate

Species Most Affected

Unknown 166
Dog 30
Cat 13
Human 4
Horse 1

Breeds Most Affected

Unknown 170
Dog (unknown) 7
Domestic Shorthair 7
Cat (unknown) 3
Dachshund (unspecified) 2
Chihuahua 2
Pit Bull 2
Bichon Frise 2
Mixed (Dog) 1
Retriever - Labrador 1

Associated Drugs

Nitenpyram 45
Cyclosporine 38
Praziquantel 24
Febantel + Praziquantel + Pyrantel Pamoate 14
Ciclesonide 12
Levothyroxine Sodium 8
Grapiprant 7
Ilunocitinib 7
Flea Collar 5
Omeprazole 3
Meloxicam 3
Gabapentin 3
Imidacloprid 3
Ivermectin + Pyrantel As Pamoate Salt 2
Afoxolaner 2
Spinosad 2
Firocoxib 2
Ivermectin + Praziquantel 2
Oclacitinib Maleate 2
Ivermectin + Pyrantel 2

Circumstance or info capable of leading to medication error Reaction Insights

214 reports name Circumstance or info capable of leading to medication error; 3 recorded a death outcome (1.4% of reported events, not a population-level mortality rate). VeDDRA code: 99810.

By species: Unknown (166 reports), Dog (30 reports), Cat (13 reports). By breed: Unknown (170), Dog (unknown) (7), Domestic Shorthair (7).

Most co-reported drugs: Nitenpyram (45 reports), Cyclosporine (38 reports), Praziquantel (24 reports), Febantel + Praziquantel + Pyrantel Pamoate (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.