Reaction profile

The FDA adverse-event record for cough, hacking

92 FDA adverse-event reports reference cough, hacking (VeDDRA 3123). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1433 of 2,481
by report volume (all reactions)
92
reports citing this reaction
16.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cough, hacking has 92 reports now versus 81 in that prior snapshot: 11 more (13.6%).

Report change
+11
Death-coded reports
+0
Death-coded share
−2.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cough, hacking changes

FDA AER · VeDDRA plate

Code 3123 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 92 reports
  • DEATH-ELEV 16.3%
  • MID-PACK #1433/2481
  • PHOTO-FINISH Bladder distension
  • SPECIES-DOG Dog · 89
  • DRUG-LEAD Bedinvetmab · 20
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bladder distension (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Cough, hacking

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bladder distension · near92Cough, hacking · this reacti…92Elevated fructosamine · near92Injection site discha… · near92Injection site tender… · near92Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cough, hacking

What the FDA AER plate says about Cough, hacking

Signature read: report volume at 92 (#1433 of 2,481) is the standout scale stamp on Cough, hacking. Report volume sits in the middle third of the reaction corpus. 15 of 92 reports were death-coded (16.3% of named reports, not a population mortality rate). Nearest volume peer: Bladder distension (±0 reports). Lead species Dog (89). Lead co-reported drug Bedinvetmab (20).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 89
Cat 3

Breeds Most Affected

Retriever - Labrador 16
Boxer (German Boxer) 5
Retriever - Golden 5
Terrier - Yorkshire 4
Pit Bull 4
Crossbred Canine/dog 4
Terrier - Boston 4
Shepherd Dog - Australian 3
Bulldog - French 2
Terrier - Bull - Staffordshire 2

Associated Drugs

Bedinvetmab 20
Ilunocitinib 13
Gabapentin 12
Moxidectin 10
Oclacitinib Maleate 10
Pyrantel Pamoate;Sarolaner 9
Carprofen 9
Doxycycline 9
Bordetella Bronchiseptica, Boehringer Ingelheim Strain 9
Maropitant Citrate 8
Fluralaner 13.64% 12-Week Chew 7
Prednisone 7
Milbemycin Oxime + Praziquantel 6
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 5
Lotilaner 4
Cefpodoxime 4
Midazolam 4
Buprenorphine 4
Ketoconazole,Hydrocortisone 4
Leptospira Canicola, Hond Urecht Strain,Leptospira Grippotyphosa, F4397 Strain,Leptospira Icterohaemorrhagiae, Copenhageni Strain,Leptospira Pomona, Kennewicki Strain 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cough, hacking, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (16.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cough, hacking (#1433 of 2,481 by report volume); death-coded 16.3%. PlainBreed reaction plate · report volume stamp 92 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →