Reaction profile

The FDA adverse-event record for meningitis

162 FDA adverse-event reports reference meningitis (VeDDRA 637). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1146 of 2,481
by report volume (all reactions)
162
reports citing this reaction
29.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Meningitis has 162 reports now versus 160 in that prior snapshot: 2 more (1.3%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Meningitis changes

FDA AER · VeDDRA plate

Code 637 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 162 reports
  • DEATH-HOT 29.0%
  • MID-PACK #1146/2481
  • PHOTO-FINISH Dazed
  • SPECIES-DOG Dog · 139
  • DRUG-LEAD Milbemycin Oxime… · 22
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dazed (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Meningitis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bronchopneumonia · near163Dazed · near162Haemolysis NOS · near162Meningitis · this reaction162Pancytopenia · near162Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Meningitis

Meningitis: high death-coded share in the FDA AER plate

Signature read: Meningitis's 29.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 47 of 162 reports (29.0% of named reports). Nearest volume peer: Dazed (±0 reports). Lead species Dog (139). Lead co-reported drug Milbemycin Oxime + Spinosad (22).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 139
Cat 14
Cattle 5
Pig 2
Horse 2

Breeds Most Affected

Retriever - Labrador 10
Crossbred Canine/dog 10
Domestic Shorthair 9
Retriever - Golden 8
Chihuahua 7
Bulldog - French 7
Poodle - Standard 5
Boxer (German Boxer) 5
Dog (unknown) 5
Mountain Dog - Bernese 5

Associated Drugs

Milbemycin Oxime + Spinosad 22
Maropitant Citrate 16
Carprofen 13
Afoxolaner 12
Pyrantel Pamoate;Sarolaner 11
Fluralaner Chew Tablets 9
Fluralaner 13.64% 12-Week Chew 9
Prednisone 8
Gabapentin 8
Moxidectin 8
Tramadol 7
Clindamycin 7
Oclacitinib Maleate 7
Anti-Il31 Mab Mcs Lot #1283563 7
Bedinvetmab 7
Spinosad 6
Cefovecin 6
Buprenorphine 6
Doxycycline 5
Ivermectin + Pyrantel As Pamoate Salt 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Meningitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (162 here).

Similar death-coded share

Nearest other reactions by death-coded share (29.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Meningitis (#1146 of 2,481 by report volume); death-coded 29.0%. PlainBreed reaction plate · death-coded share stamp 29.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →