Reaction profile

The FDA adverse-event record for implant, abnormal

318 FDA adverse-event reports reference implant, abnormal (VeDDRA 99013). See the species, breeds, and drugs most associated with it below.

318
reports citing this reaction
0.6%
death-coded share
Unknown
most-affected species
Deslorelin Acetate
most-associated drug
Verify with FDA CVM →
318
Total Reports
2
Deaths
0.6%
Death Rate

Species Most Affected

Unknown 290
Cattle 25
Ferret 3

Breeds Most Affected

Unknown 290
Cattle (unknown) 13
Mixed (Cattle) 9
Domestic ferret (Pet ferret) 3
Holstein-Friesian also known as Holstein 2
Aberdeen Angus 1

Associated Drugs

Deslorelin Acetate 68
Deslorelin 63
Zeranol 61
Estradiol, Trenbolone Acetate 23
Trenbolone Acet/Estradiol Impl 20
Trenbolone Acetate;Estradiol Benzoate 18
Estradiol Benzoate; Trenbolone Acetate 14
Estradiol Benzoate, Progesterone 8
Progesterone;Estradiol Benzoate 8
Progesterone 6
Progesterone; Estradiol Benzoate 6
Trenbolone Acet/Estrad Sr Imp 6
Zeranol Implant 5
Estradiol, Testosterone 3
Estradiol + Trenbolone 3
Estradiol 3
Synovex One Sx-10 Applicator 2
Testosterone Propionate;Estradiol Benzoate 2
Estradiol + Progesterone 1
Testosterone; Estradiol Benzoate; Tylosin Tartrate 1

Implant, Abnormal Reaction Insights

318 reports name Implant, Abnormal; 2 recorded a death outcome (0.6% of reported events, not a population-level mortality rate). VeDDRA code: 99013.

By species: Unknown (290 reports), Cattle (25 reports), Ferret (3 reports). By breed: Unknown (290), Cattle (unknown) (13), Mixed (Cattle) (9).

Most co-reported drugs: Deslorelin Acetate (68 reports), Deslorelin (63 reports), Zeranol (61 reports), Estradiol, Trenbolone Acetate (23 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.