Pneumothorax

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VeDDRA Code: 2035

32 adverse event reports referencing this reaction

32
Total Reports
19
Deaths
5940.0%
Death Rate

Species Most Affected

Dog 19
Cat 12
Cattle 1

Breeds Most Affected

Domestic Shorthair 8
Shepherd Dog - German 3
Crossbred Canine/dog 2
Retriever - Labrador 2
Persian 1
Retriever - Golden 1
Poodle - Toy 1
Weimaraner 1
Shih Tzu 1
Akita 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Metronidazole 5
Maropitant Citrate 4
Famotidine 4
Furosemide 4
Oclacitinib Maleate 3
Methylprednisolone Acetate 3
Isoflurane 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 2
Diphenhydramine Hcl 2
Sucralfate 2
Pyrantel Pamoate 2
Cefovecin 2
Deracoxib 2
Midazolam 2
Fluralaner Chew Tablets 2
Alfaxalone 2
Dexamethasone 2
Unknown Brand Flea Collar 2

Data Summary

Metric Value
Total reports referencing reaction 32
Reports with fatal outcome 19
Case-fatality rate (reported events) 5940.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2035.

Pneumothorax Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 32 adverse event reports that reference Pneumothorax as a reaction term, including 19 reports with a death outcome — a 5940.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2035, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pneumothorax appears most frequently in reports for Dog (19 reports), Cat (12 reports), Cattle (1 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (8), Shepherd Dog - German (3), Crossbred Canine/dog (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pneumothorax are Milbemycin Oxime + Spinosad (6 reports), Metronidazole (5 reports), Maropitant Citrate (4 reports), Famotidine (4 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 6 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial