Reaction profile

The FDA adverse-event record for pneumothorax

32 FDA adverse-event reports reference pneumothorax (VeDDRA 2035). See the species, breeds, and drugs most associated with it below.

32
reports citing this reaction
59.4%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
32
Total Reports
19
Deaths
59.4%
Death Rate

Species Most Affected

Dog 19
Cat 12
Cattle 1

Breeds Most Affected

Domestic Shorthair 8
Shepherd Dog - German 3
Crossbred Canine/dog 2
Retriever - Labrador 2
Persian 1
Retriever - Golden 1
Poodle - Toy 1
Weimaraner 1
Shih Tzu 1
Akita 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Metronidazole 5
Maropitant Citrate 4
Famotidine 4
Furosemide 4
Oclacitinib Maleate 3
Methylprednisolone Acetate 3
Isoflurane 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 2
Diphenhydramine Hcl 2
Sucralfate 2
Pyrantel Pamoate 2
Cefovecin 2
Deracoxib 2
Midazolam 2
Fluralaner Chew Tablets 2
Alfaxalone 2
Dexamethasone 2
Unknown Brand Flea Collar 2

Pneumothorax Reaction Insights

32 reports name Pneumothorax; 19 recorded a death outcome (59.4% of reported events, not a population-level mortality rate). VeDDRA code: 2035.

By species: Dog (19 reports), Cat (12 reports), Cattle (1 reports). By breed: Domestic Shorthair (8), Shepherd Dog - German (3), Crossbred Canine/dog (2).

Most co-reported drugs: Milbemycin Oxime + Spinosad (6 reports), Metronidazole (5 reports), Maropitant Citrate (4 reports), Famotidine (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.