Reaction profile

The FDA adverse-event record for application site discharge nos

45 FDA reports name application site discharge nos, a lower-volume reaction in the CVM extract (VeDDRA 3051). Plate stamps and neighbourhood peers follow.

#1791 of 2,481
by report volume (all reactions)
45
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Application site discharge NOS has 45 reports now versus 34 in that prior snapshot: 11 more (32.4%).

Report change
+11
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Application site discharge NOS changes

FDA AER · VeDDRA plate

Code 3051 VOL-TRACE

VOL-TRACE · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 45 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1791/2481
  • PHOTO-FINISH Buccal irritation
  • SPECIES-DOG Dog · 31
  • DRUG-LEAD Genta/Posacon/Mom… · 13
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Buccal irritation (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Application site discharge NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site disc… · thi…45Buccal irritation · near45Chest tightness · near45Flaccid paralysis · near45Lacrimation increased · near45Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Application site discharge NOS

Application site discharge NOS: low death-coded share in the FDA AER plate

Signature read: Application site discharge NOS's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 45 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 45 reports (0.0% of named reports). Nearest volume peer: Buccal irritation (±0 reports). Lead species Dog (31). Lead co-reported drug Genta/Posacon/Mometa Eardrops (13).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Genta/Posacon/Mometa Eardrops appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 31
Cat 12
Horse 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 9
Crossbred Canine/dog 7
Retriever - Golden 5
Retriever - Labrador 5
Dog (unknown) 2
Bulldog - English 2
Maltese 2
Boxer (German Boxer) 1
Quarter Horse 1
Chihuahua 1

Associated Drugs

Genta/Posacon/Mometa Eardrops 13
Tigilanol Tiglate 5
Terbinafine, Betamethasone Acetate 4
Florfenicol, Terbinafine, Betamethasone Acetate 3
Dexmedetomidine 3
Selamectin;Sarolaner 3
Polyglactin 910 2
Ear Cleaner 2
Butorphanol 2
Maropitant Citrate 2
Gentamicin Sulfate, Usp; Mometasone Furoate Anhydrous, Usp; Clotrimazole, Usp 2
Lokivetmab 2
0.15% Ketoconazole In Usp Trizedta 2
Buprenorphine 2
Neomycin/Polymyxin B/Dexamethasone Ophthalmic Solution 2
Imidacloprid, Moxidectin 1
Imidacloprid, Flumethrin 1
Imidacloprid + Moxidectin 1
Trazodone 1
Antibiotic (Unknown) 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Application site discharge NOS (#1791 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →