Reaction profile

The FDA adverse-event record for synovitis

64 FDA adverse-event reports reference synovitis (VeDDRA 623). See the species, breeds, and drugs most associated with it below.

64
reports citing this reaction
9.4%
death-coded share
Horse
most-affected species
Hyaluronate Sodium
most-associated drug
Verify with FDA CVM →
64
Total Reports
6
Deaths
9.4%
Death Rate

Species Most Affected

Horse 40
Dog 21
Chicken 1
Turkey 1
Cat 1

Breeds Most Affected

Horse (unknown) 9
Quarter Horse 8
Retriever - Labrador 7
Warmblood (unspecified) 6
Thoroughbred 6
Crossbred Equine/horse 3
Shepherd Dog - German 3
Horse (other) 2
Warmblood - Dutch 2
Standardbred (unspecified) 1

Associated Drugs

Hyaluronate Sodium 21
Bedinvetmab 13
Methylprednisolone Acetate 9
Triamcinolone Acetonide 7
Oclacitinib Maleate 4
Carprofen 4
Gabapentin 4
Hyaluronate Sodium 10 Mg/Ml Solution For Injection 3
Amoxicillin/Clavulanic Acid 3
Galliprant 3
Grapiprant 3
Hyaluronic Acid 2
Dapp Vaccine 2
Phenobarbital 2
Levetiracetam 2
Prednisone 2
Trazodone 2
Nexgard Plus 2
Movoflex 2
Mepivacaine Hydrochloride 1

Synovitis Reaction Insights

64 reports name Synovitis; 6 recorded a death outcome (9.4% of reported events, not a population-level mortality rate). VeDDRA code: 623.

By species: Horse (40 reports), Dog (21 reports), Chicken (1 reports). By breed: Horse (unknown) (9), Quarter Horse (8), Retriever - Labrador (7).

Most co-reported drugs: Hyaluronate Sodium (21 reports), Bedinvetmab (13 reports), Methylprednisolone Acetate (9 reports), Triamcinolone Acetonide (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.