Reaction profile

The FDA adverse-event record for cranial nerve disorder

98 FDA adverse-event reports reference cranial nerve disorder (VeDDRA 1147). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1404 of 2,481
by report volume (all reactions)
98
reports citing this reaction
33.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cranial nerve disorder has 98 reports now versus 98 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cranial nerve disorder changes

FDA AER · VeDDRA plate

Code 1147 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 98 reports
  • DEATH-HOT 33.7%
  • MID-PACK #1404/2481
  • PHOTO-FINISH Acting tense
  • SPECIES-DOG Dog · 77
  • DRUG-LEAD Milbemycin Oxime… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acting tense (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Cranial nerve disorder

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acting tense · near98Cranial nerve disorder · thi…98INEFFECTIVE, LICE SUC… · near98Product syringe impro… · near98Digestive tract steno… · near97Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cranial nerve disorder

Cranial nerve disorder: high death-coded share in the FDA AER plate

Signature read: Cranial nerve disorder's 33.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 33 of 98 reports (33.7% of named reports). Nearest volume peer: Acting tense (±0 reports). Lead species Dog (77). Lead co-reported drug Milbemycin Oxime + Spinosad (15).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 77
Cat 14
Horse 6
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 9
Domestic Shorthair 9
Boxer (German Boxer) 7
Chihuahua 5
Maltese 5
Terrier - Yorkshire 4
Pug 3
Retriever - Labrador 3
Bulldog 3
Pit Bull 3

Associated Drugs

Milbemycin Oxime + Spinosad 15
Moxidectin 10
Prednisone 9
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Gabapentin 8
Bedinvetmab 8
Spinosad 6
Maropitant Citrate 6
Fluid Therapy 6
Fluralaner Chew Tablets 5
Enrofloxacin 5
Carprofen 5
Ceftiofur Crystalline Free Acid 4
Butorphanol 4
Phenobarbital 4
Oclacitinib Maleate 4
Doxycycline 4
Buprenorphine 4
Diphenhydramine Injection 4
Cyclosporine 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cranial nerve disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (33.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cranial nerve disorder (#1404 of 2,481 by report volume); death-coded 33.7%. PlainBreed reaction plate · death-coded share stamp 33.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →