Reaction profile

The FDA adverse-event record for hypomagnesaemic condition

123 FDA adverse-event reports reference hypomagnesaemic condition (VeDDRA 564). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1291 of 2,481
by report volume (all reactions)
123
reports citing this reaction
26.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypomagnesaemic condition has 123 reports now versus 120 in that prior snapshot: 3 more (2.5%).

Report change
+3
Death-coded reports
+2
Death-coded share
+1.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypomagnesaemic condition changes

FDA AER · VeDDRA plate

Code 564 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 123 reports
  • DEATH-HOT 26.0%
  • MID-PACK #1291/2481
  • PHOTO-FINISH Birth defect
  • SPECIES-DOG Dog · 99
  • DRUG-LEAD Milbemycin Oxime… · 18
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Birth defect (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Hypomagnesaemic condition

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Birth defect · near123Hypomagnesaemic condi… · thi…123Joint ligament disord… · near123Lens disorder NOS · near123Lung tumour · near123Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypomagnesaemic condition

Hypomagnesaemic condition: high death-coded share in the FDA AER plate

Signature read: Hypomagnesaemic condition's 26.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 32 of 123 reports (26.0% of named reports). Nearest volume peer: Birth defect (±0 reports). Lead species Dog (99). Lead co-reported drug Milbemycin Oxime + Spinosad (18).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 99
Cat 13
Cattle 7
Horse 3
Human 1

Breeds Most Affected

Domestic Shorthair 9
Retriever - Labrador 8
Crossbred Canine/dog 8
Shih Tzu 5
Retriever - Golden 4
Terrier - Tibetan 3
Mastiff 3
Dog (other) 3
Domestic Longhair 3
Holstein-Friesian also known as Holstein 3

Associated Drugs

Milbemycin Oxime + Spinosad 18
Trilostane 11
Oclacitinib Maleate 8
Maropitant Citrate 7
Cyclosporine 6
Ivermectin + Pyrantel As Pamoate Salt 6
Spinosad 5
Carprofen 5
Afoxolaner 5
Velagliflozin Proline Monohydrate 5
Enrofloxacin 4
Milbemycin Oxime 4
Sucralfate 4
Meloxicam 4
Fluralaner Chew Tablets 4
Pantoprazole 4
Ondansetron 4
Gabapentin 4
Moxidectin 3
Cefovecin 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hypomagnesaemic condition, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (123 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypomagnesaemic condition (#1291 of 2,481 by report volume); death-coded 26.0%. PlainBreed reaction plate · death-coded share stamp 26.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →