Lethargy (see also Central nervous system depression in 'Neurological')
VeDDRA Code: 1018
75,886 adverse event reports referencing this reaction
75,886
Total Reports
6,399
Deaths
840.0%
Death Rate
Species Most Affected
Dog 65,152
Cat 9,864
Horse 417
Cattle 199
Human 50
Pig 47
Unknown 27
Rabbit 24
Goat 15
Sheep 14
Breeds Most Affected
Domestic Shorthair 5,954
Retriever - Labrador 5,869
Crossbred Canine/dog 4,285
Chihuahua 3,541
Terrier - Yorkshire 2,984
Retriever - Golden 2,730
Shih Tzu 2,587
Boxer (German Boxer) 2,285
Maltese 1,928
Shepherd Dog - German 1,860
Associated Drugs
Milbemycin Oxime + Spinosad 20,659
Spinosad 5,205
Afoxolaner 5,200
Moxidectin 3,738
Fluralaner Chew Tablets 3,354
Ivermectin + Pyrantel As Pamoate Salt 3,049
Carprofen 2,794
Trilostane 2,678
Imidacloprid + Moxidectin 2,397
Selamectin 2,293
Maropitant Citrate 2,284
Oclacitinib Maleate 2,121
Pyrantel Pamoate;Sarolaner 1,983
Milbemycin Oxime + Praziquantel 1,799
Cefovecin 1,758
Sarolaner 1,592
Nitenpyram 1,290
Prednisone 1,163
Fluralaner 13.64% 12-Week Chew 1,121
Fluralaner Spot-On Solution 1,058
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.