Yellow mucous membranes

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VeDDRA Code: 500

85 adverse event reports referencing this reaction

85
Total Reports
43
Deaths
5060.0%
Death Rate

Species Most Affected

Dog 69
Cat 14
Horse 1
Sheep 1

Breeds Most Affected

Retriever - Labrador 15
Domestic Shorthair 11
Siberian Husky 4
Bulldog 4
Dachshund (unspecified) 4
Retriever - Golden 3
Crossbred Canine/dog 3
Pug 3
Corgi - Welsh Pembroke 3
Beagle 2

Associated Drugs

Carprofen 27
Maropitant Citrate 13
Famotidine 7
Gabapentin 6
Moxidectin 5
Oclacitinib Maleate 5
Fluralaner Chew Tablets 5
Milbemycin Oxime + Spinosad 4
Ampicillin 4
Itraconazole 4
Buprenorphine 4
Enrofloxacin 3
Cefovecin 3
Diphenhydramine Hcl 3
Anesthetic 3
Rabies Vaccine 3
Doxycycline 3
Sam-E, Silybin, Vitamin E, Zinc 3
Antibiotic 3
Tramadol 3

Data Summary

Metric Value
Total reports referencing reaction 85
Reports with fatal outcome 43
Case-fatality rate (reported events) 5060.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 500.

Yellow mucous membranes Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 85 adverse event reports that reference Yellow mucous membranes as a reaction term, including 43 reports with a death outcome — a 5060.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 500, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Yellow mucous membranes appears most frequently in reports for Dog (69 reports), Cat (14 reports), Horse (1 reports) — with Dog dominating at 69 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (15), Domestic Shorthair (11), Siberian Husky (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Yellow mucous membranes are Carprofen (27 reports), Maropitant Citrate (13 reports), Famotidine (7 reports), Gabapentin (6 reports), with Carprofen appearing alongside this reaction in 27 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial