Digestive tract hypomotility

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VeDDRA Code: 2163

126 adverse event reports referencing this reaction

126
Total Reports
31
Deaths
2460.0%
Death Rate

Species Most Affected

Dog 92
Horse 18
Cat 13
Cattle 2
Donkey 1

Breeds Most Affected

Retriever - Labrador 11
Domestic (unspecified) 9
Chihuahua 6
Dog (unknown) 6
Retriever - Golden 6
Bulldog 5
Warmblood (unspecified) 4
Terrier - Yorkshire 3
Shepherd Dog - Australian 3
Quarter Horse 3

Associated Drugs

Maropitant 31
Maropitant Citrate 22
Carprofen 8
Metronidazole 7
Milbemycin Oxime + Spinosad 7
Firocoxib 6
Enrofloxacin 6
Moxidectin 5
Famotidine 5
Oclacitinib Maleate 4
Cephalexin 4
Fenbendazole 4
Buprenorphine 4
Metoclopramide 4
Milbemycin Oxime 4
Spinosad 3
Meloxicam 3
Detomidine 3
Amoxicillin 3
Dexamethasone Sodium Phosphate 3

Data Summary

Metric Value
Total reports referencing reaction 126
Reports with fatal outcome 31
Case-fatality rate (reported events) 2460.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2163.

Digestive tract hypomotility Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 126 adverse event reports that reference Digestive tract hypomotility as a reaction term, including 31 reports with a death outcome — a 2460.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2163, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Digestive tract hypomotility appears most frequently in reports for Dog (92 reports), Horse (18 reports), Cat (13 reports) — with Dog dominating at 92 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Domestic (unspecified) (9), Chihuahua (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Digestive tract hypomotility are Maropitant (31 reports), Maropitant Citrate (22 reports), Carprofen (8 reports), Metronidazole (7 reports), with Maropitant appearing alongside this reaction in 31 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial