Reaction profile

The FDA adverse-event record for reverse sneezing

291 FDA adverse-event reports reference reverse sneezing (VeDDRA 2178). See the species, breeds, and drugs most associated with it below.

291
reports citing this reaction
5.5%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
291
Total Reports
16
Deaths
5.5%
Death Rate

Species Most Affected

Dog 287
Cat 4

Breeds Most Affected

Chihuahua 36
Crossbred Canine/dog 27
Beagle 15
Maltese 15
Shih Tzu 13
Spitz - German Pomeranian 12
Havanese 11
Terrier - Yorkshire 10
Retriever - Labrador 9
Terrier - Jack Russell 8

Associated Drugs

Oclacitinib Maleate 36
Milbemycin Oxime + Spinosad 32
Milbemycin Oxime + Praziquantel 25
Afoxolaner 21
Maropitant Citrate 21
Pyrantel Pamoate;Sarolaner 18
Ivermectin + Pyrantel As Pamoate Salt 17
Fluralaner Chew Tablets 14
Prednisone 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 12
Pimobendan 10
Moxidectin 10
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim;Canine Adenov 10
Gabapentin 9
Fluralaner 13.64% 12-Week Chew 9
Carprofen 8
Canine Bb/Pi3/Adeno 2 Lv/Lb 7
Imidacloprid + Moxidectin 7
Metronidazole 7
Trilostane 7

Reverse sneezing Reaction Insights

291 reports name Reverse sneezing; 16 recorded a death outcome (5.5% of reported events, not a population-level mortality rate). VeDDRA code: 2178.

By species: Dog (287 reports), Cat (4 reports). By breed: Chihuahua (36), Crossbred Canine/dog (27), Beagle (15).

Most co-reported drugs: Oclacitinib Maleate (36 reports), Milbemycin Oxime + Spinosad (32 reports), Milbemycin Oxime + Praziquantel (25 reports), Afoxolaner (21 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.