Reaction profile

The FDA adverse-event record for urinary tract neoplasm

93 FDA adverse-event reports reference urinary tract neoplasm (VeDDRA 742). See the species, breeds, and drugs most associated with it below.

93
reports citing this reaction
43.0%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
93
Total Reports
40
Deaths
43.0%
Death Rate

Species Most Affected

Dog 86
Cat 6
Horse 1

Breeds Most Affected

Beagle 6
Crossbred Canine/dog 6
Terrier - Scottish 6
Retriever - Labrador 5
Sheepdog - Shetland 4
Terrier - West Highland White 4
Terrier - Yorkshire 4
Siberian Husky 3
Boxer (German Boxer) 3
Cat (unknown) 2

Associated Drugs

Oclacitinib Maleate 25
Trilostane 23
Milbemycin Oxime + Spinosad 11
Afoxolaner 5
Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 4
Spinosad And Milbemycin Oxime 4
Carprofen 4
Grapiprant 4
Maropitant Citrate 3
Anesthetic 3
Cyclosporine 2
Cefovecin Sodium 2
Meloxicam 2
Lufenuron + Milbemycin Oxime 2
Tramadol 2
Ivermectin + Pyrantel 2
Ketoconazole 2
Glucosamine, Chondroitin, Unsaponifiables 2
Cetirizine Hcl 2

Urinary tract neoplasm Reaction Insights

93 reports name Urinary tract neoplasm; 40 recorded a death outcome (43.0% of reported events, not a population-level mortality rate). VeDDRA code: 742.

By species: Dog (86 reports), Cat (6 reports), Horse (1 reports). By breed: Beagle (6), Crossbred Canine/dog (6), Terrier - Scottish (6).

Most co-reported drugs: Oclacitinib Maleate (25 reports), Trilostane (23 reports), Milbemycin Oxime + Spinosad (11 reports), Afoxolaner (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.