Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - cooperia

36 FDA reports name lack of efficacy (endoparasite) - cooperia, a lower-volume reaction in the CVM extract (VeDDRA 2795). Plate stamps and neighbourhood peers follow.

#1911 of 2,481
by report volume (all reactions)
36
reports citing this reaction
5.6%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (endoparasite) - Cooperia has 36 reports now versus 36 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (endoparasite) - Cooperia changes

FDA AER · VeDDRA plate

Code 2795 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 36 reports
  • DEATH-PAR 5.6%
  • LOWER-Q #1911/2481
  • PHOTO-FINISH Abnormal birth weight
  • SPECIES-CATTLE Cattle · 24
  • DRUG-LEAD Eprinomectin · 20
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal birth weight (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - Cooperia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal birth weight · near36Adaptor, leaking · near36Blood dyscrasia NOS · near36Contact dermatitis · near36Lack of efficacy (end… · thi…36Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (endoparasite) - Cooperia

Lack of efficacy (endoparasite) - Cooperia: low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Lack of efficacy (endoparasite) - Cooperia in the CVM extract. Report volume is lower-third scale: 36 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 36 reports (5.6% of named reports). Nearest volume peer: Abnormal birth weight (±0 reports). Lead species Cattle (24). Lead co-reported drug Eprinomectin (20).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Eprinomectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 24
Dog 12

Breeds Most Affected

Cattle (other) 10
Aberdeen Angus 6
Cattle (unknown) 4
Retriever - Labrador 3
Terrier - Bull - American Pit 2
Crossbred Bovine/Cattle 2
Saint Bernard Dog 1
Brahman 1
Spaniel (unspecified) 1
Mixed (Dog) 1

Associated Drugs

Eprinomectin 20
Pyrantel Pamoate;Sarolaner 12
Oxfendazole 3
Fenbendazol Suspension 2
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Campylobacter Fetus Bacterin + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 1
Bacterin 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid + Moraxella Bovis Bacterin Toxoid 1
Fenbendazole 1
Fenbendazol Pellets 1
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid 1
Clorsulon + Ivermectin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (endoparasite) - Cooperia (#1911 of 2,481 by report volume); death-coded 5.6%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →