Reaction profile

The FDA adverse-event record for injected sclera

234 FDA adverse-event reports reference injected sclera (VeDDRA 2462). See the species, breeds, and drugs most associated with it below.

234
reports citing this reaction
10.7%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
234
Total Reports
25
Deaths
10.7%
Death Rate

Species Most Affected

Dog 214
Cat 17
Horse 3

Breeds Most Affected

Retriever - Labrador 15
Shih Tzu 11
Boxer (German Boxer) 11
Chihuahua 11
Terrier - Bull - American Pit 11
Domestic Shorthair 10
Crossbred Canine/dog 9
Terrier - Yorkshire 9
Beagle 7
Retriever - Golden 6

Associated Drugs

Moxidectin 44
Carprofen 19
Maropitant Citrate 17
Prednisone 16
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 15
Afoxolaner 14
Trilostane 13
Oclacitinib Maleate 12
Sarolaner 11
Pyrantel Pamoate;Sarolaner 11
Bedinvetmab 11
Gabapentin 10
Isoflurane 9
Diphenhydramine 8
Midazolam 8
Verdinexor 8
Fluralaner Chew Tablets 7
Selamectin 7
Fluralaner 7
Doxycycline 7

Injected sclera Reaction Insights

234 reports name Injected sclera; 25 recorded a death outcome (10.7% of reported events, not a population-level mortality rate). VeDDRA code: 2462.

By species: Dog (214 reports), Cat (17 reports), Horse (3 reports). By breed: Retriever - Labrador (15), Shih Tzu (11), Boxer (German Boxer) (11).

Most co-reported drugs: Moxidectin (44 reports), Carprofen (19 reports), Maropitant Citrate (17 reports), Prednisone (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.