Reaction profile

The FDA adverse-event record for eye itching

192 FDA adverse-event reports reference eye itching (VeDDRA 1457). See the species, breeds, and drugs most associated with it below.

192
reports citing this reaction
1.6%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
192
Total Reports
3
Deaths
1.6%
Death Rate

Species Most Affected

Dog 131
Human 43
Cat 15
Horse 3

Breeds Most Affected

Unknown 43
Crossbred Canine/dog 12
Dog (unknown) 8
Chihuahua 7
Domestic Shorthair 7
Retriever - Labrador 7
Shih Tzu 7
Retriever - Golden 6
Schnauzer - Miniature 4
Bulldog 4

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 17
Moxidectin 13
Milbemycin Oxime + Spinosad 12
Imidacloprid + Moxidectin 11
Selamectin 11
Oclacitinib Maleate 9
Carprofen 9
Afoxolaner 9
Milbemycin Oxime + Praziquantel 9
Prednisone 8
Pyrantel Pamoate;Sarolaner 8
Maropitant Citrate 7
Lotilaner 6
Fluralaner Chew Tablets 5
Gabapentin 5
Doxycycline 5
Ivermectin + Pyrantel As Pamoate Salt 4
Polymyxin B Sulfate;Oxytetracycline Hcl 4
Frunevetmab 4
Spinosad 3

Eye itching Reaction Insights

192 reports name Eye itching; 3 recorded a death outcome (1.6% of reported events, not a population-level mortality rate). VeDDRA code: 1457.

By species: Dog (131 reports), Human (43 reports), Cat (15 reports). By breed: Unknown (43), Crossbred Canine/dog (12), Dog (unknown) (8).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (17 reports), Moxidectin (13 reports), Milbemycin Oxime + Spinosad (12 reports), Imidacloprid + Moxidectin (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.