Reaction profile

The FDA adverse-event record for tendon rupture

Name: Tendon rupture - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

31 FDA reports name tendon rupture, a lower-volume reaction in the CVM extract (VeDDRA 627). Plate stamps and neighbourhood peers follow.

#1985 of 2,481
by report volume (all reactions): 31
reports citing this reaction: 9.7%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tendon rupture has 31 reports now versus 27 in that prior snapshot: 4 more (14.8%).

Report change: +4
Death-coded reports: +2
Death-coded share: +6.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tendon rupture changes

FDA AER · VeDDRA plate

Code 627 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 31 reports
DEATH-PAR 9.7%
LOWER-Q #1985/2481
PHOTO-FINISH ABNORMAL TEST RESULT,…
SPECIES-DOG Dog · 19
DRUG-LEAD Frunevetmab · 10
DESK-WIDE 16 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Tendon rupture

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Tendon rupture

What the FDA AER plate says about Tendon rupture

Signature read: 31 reports place Tendon rupture in the lower third of FDA AER volume (#1985 of 2,481). Report volume is lower-third scale: 31 named reports in the openFDA extract. 3 of 31 reports were death-coded (9.7% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (19). Lead co-reported drug Frunevetmab (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Frunevetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 19

Cat 12

Breeds Most Affected

Domestic Shorthair 7

Retriever - Labrador 6

Terrier (unspecified) 3

Domestic Mediumhair 3

Terrier - Border 1

Retriever - Golden 1

Brittany 1

Siberian Husky 1

Bloodhound 1

Pit Bull 1

Associated Drugs

Frunevetmab 10

Gabapentin 5

Bedinvetmab 5

Milbemycin Oxime + Spinosad 4

Meloxicam 4

Enrofloxacin 3

Buprenorphine 3

Maropitant Citrate 3

Unknown Medication 3

Probiotics 3

Trilostane 2

Marbofloxacin 2

Polysulfated Glycosaminoglycan 2

Milbemycin Oxime + Praziquantel 2

Diphenhydramine 2

Galliprant 2

Mirtazapine 2

Lactulose 2

Prednisolone 2

Amlodipine 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tendon rupture (#1985 of 2,481 by report volume); death-coded 9.7%. PlainBreed reaction plate · report volume stamp 31 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →