Reaction profile

The FDA adverse-event record for polycythemia, relative

100 FDA adverse-event reports reference polycythemia, relative (VeDDRA 99318). See the species, breeds, and drugs most associated with it below.

100
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species
Spinosad
most-associated drug
Verify with FDA CVM →
100
Total Reports
20
Deaths
20.0%
Death Rate

Species Most Affected

Dog 93
Cat 7

Breeds Most Affected

Crossbred Canine/dog 21
Retriever - Labrador 6
Shepherd Dog - German 5
Terrier - Yorkshire 5
Terrier - Jack Russell 4
Domestic (unspecified) 4
Retriever - Golden 4
Maltese 4
Beagle 3
Poodle (unspecified) 3

Associated Drugs

Spinosad 21
Deracoxib 11
Carprofen 10
Moxidectin 10
Cyclosporine 8
Meloxicam 7
Firocoxib 5
Maropitant Citrate 5
Milbemycin 4
Melarsomine Dihydrochloride 4
Trilostane 4
Isoflurane 4
Cefovecin Sodium 3
Maropitant 3
Tramadol 3
Acepromazine Maleate 3
Buprenorphine 3
Ivermectin, Pyrantel Pamoate, Praziquantel 2
Milbemycin, Lufenuron 2
Hydromorphone Hcl 2

POLYCYTHEMIA, RELATIVE Reaction Insights

100 reports name POLYCYTHEMIA, RELATIVE; 20 recorded a death outcome (20.0% of reported events, not a population-level mortality rate). VeDDRA code: 99318.

By species: Dog (93 reports), Cat (7 reports). By breed: Crossbred Canine/dog (21), Retriever - Labrador (6), Shepherd Dog - German (5).

Most co-reported drugs: Spinosad (21 reports), Deracoxib (11 reports), Carprofen (10 reports), Moxidectin (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.