Reaction profile

The FDA adverse-event record for polycythemia, relative

100 FDA adverse-event reports reference polycythemia, relative (VeDDRA 99318). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1401 of 2,481
by report volume (all reactions)
100
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. POLYCYTHEMIA, RELATIVE has 100 reports now versus 100 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to POLYCYTHEMIA, RELATIVE changes

FDA AER · VeDDRA plate

Code 99318 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 100 reports
  • DEATH-HOT 20.0%
  • MID-PACK #1401/2481
  • PHOTO-FINISH Circulatory shock
  • SPECIES-DOG Dog · 93
  • DRUG-LEAD Spinosad · 21
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Circulatory shock (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around POLYCYTHEMIA, RELATIVE

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Circulatory shock · near100Elevated ALT · near100Impaired swallowing · near100Lymphosarcoma · near100POLYCYTHEMIA, RELATIVE · thi…100Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around POLYCYTHEMIA, RELATIVE

What the FDA AER plate says about POLYCYTHEMIA, RELATIVE

Signature read: death-coded share at 20.0% is the most distinctive outcome stamp on POLYCYTHEMIA, RELATIVE. Report volume sits in the middle third of the reaction corpus. 20 of 100 reports were death-coded (20.0% of named reports, not a population mortality rate). Nearest volume peer: Circulatory shock (±0 reports). Lead species Dog (93). Lead co-reported drug Spinosad (21).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 93
Cat 7

Breeds Most Affected

Crossbred Canine/dog 21
Retriever - Labrador 6
Shepherd Dog - German 5
Terrier - Yorkshire 5
Domestic (unspecified) 4
Terrier - Jack Russell 4
Retriever - Golden 4
Maltese 4
Beagle 3
Poodle (unspecified) 3

Associated Drugs

Spinosad 21
Deracoxib 11
Carprofen 10
Moxidectin 10
Cyclosporine 8
Meloxicam 7
Firocoxib 5
Maropitant Citrate 5
Milbemycin 4
Melarsomine Dihydrochloride 4
Isoflurane 4
Trilostane 4
Cefovecin Sodium 3
Maropitant 3
Tramadol 3
Acepromazine Maleate 3
Buprenorphine 3
Milbemycin, Lufenuron 2
Ivermectin, Pyrantel Pamoate, Praziquantel 2
Hydromorphone Hcl 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for POLYCYTHEMIA, RELATIVE, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (100 here).

Similar death-coded share

Nearest other reactions by death-coded share (20.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for POLYCYTHEMIA, RELATIVE (#1401 of 2,481 by report volume); death-coded 20.0%. PlainBreed reaction plate · death-coded share stamp 20.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →