Reaction profile

The FDA adverse-event record for ruminal bloat

181 FDA adverse-event reports reference ruminal bloat (VeDDRA 320). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1086 of 2,481
by report volume (all reactions)
181
reports citing this reaction
87.8%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ruminal bloat has 181 reports now versus 181 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ruminal bloat changes

FDA AER · VeDDRA plate

Code 320 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 181 reports
  • DEATH-HOT 87.8%
  • MID-PACK #1086/2481
  • PHOTO-FINISH Acidic urine
  • SPECIES-CATTLE Cattle · 161
  • DRUG-LEAD Monensin Sodium · 81
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acidic urine (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Ruminal bloat

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Mammary gland disorde… · near182Acidic urine · near181Ruminal bloat · this reaction181Third eyelid extrusion · near181Mastitis NOS · near180Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ruminal bloat

Ruminal bloat: high death-coded share in the FDA AER plate

Signature read: Ruminal bloat's 87.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 159 of 181 reports (87.8% of named reports). Nearest volume peer: Acidic urine (±0 reports). Lead species Cattle (161). Lead co-reported drug Monensin Sodium (81).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 161
Dog 14
Goat 4
Sheep 2

Breeds Most Affected

Cattle (unknown) 43
Crossbred Bovine/Cattle 29
Cattle (other) 29
Mixed (Cattle) 17
Aberdeen Angus 15
Holstein-Friesian also known as Holstein 14
Jersey 5
Hereford cattle 4
Boer 2
Beefmaster 2

Associated Drugs

Monensin Sodium 81
Ractopamine Hydrochloride 36
Tylosin Phosphate 27
Tulathromycin 20
Monensin 10
Lasalocid Sodium 9
Trenbolone; Estradiol; Tylosin Tartrate 8
Florfenicol 8
Ceftiofur 8
Doramectin 7
Enrofloxacin 6
Tildipirosin 6
Extended Release Trenbolone Acetate And Estradiol Implant 6
Ivermectin 5
Lubabegron 5
Danofloxacin 5
Lubabegron Fumarate 5
Moxidectin 4
Zilpaterol 4
Milbemycin Oxime + Spinosad 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ruminal bloat, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (181 here).

Similar death-coded share

Nearest other reactions by death-coded share (87.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ruminal bloat (#1086 of 2,481 by report volume); death-coded 87.8%. PlainBreed reaction plate · death-coded share stamp 87.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →