Reaction profile

The FDA adverse-event record for oral bleeding

566 FDA reports name oral bleeding, a high-volume reaction in the CVM extract (VeDDRA 297). Plate stamps and neighbourhood peers follow.

#596 of 2,481
by report volume (all reactions)
566
reports citing this reaction
44.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Oral bleeding has 566 reports now versus 562 in that prior snapshot: 4 more (0.7%).

Report change
+4
Death-coded reports
+4
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Oral bleeding changes

FDA AER · VeDDRA plate

Code 297 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 566 reports
  • DEATH-HOT 44.3%
  • UPPER-Q #596/2481
  • PHOTO-FINISH Joint pain
  • SPECIES-DOG Dog · 430
  • DRUG-LEAD Carprofen · 81
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Joint pain (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Oral bleeding

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Head down · near571Joint pain · near566Mass NOS · near566Oral bleeding · this reaction566Regenerative anaemia · near566Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Oral bleeding

Oral bleeding: high death-coded share in the FDA AER plate

Signature read: 251 death-coded reports is a heavy tail count for Oral bleeding in the CVM extract. Report volume is upper-third scale: 566 named reports in the openFDA extract. Death-coded share is upper-third: 251 of 566 reports (44.3% of named reports). Nearest volume peer: Joint pain (±0 reports). Lead species Dog (430). Lead co-reported drug Carprofen (81).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 430
Cat 111
Horse 13
Cattle 9
Human 1
Ferret 1
Hedgehog 1

Breeds Most Affected

Domestic Shorthair 61
Crossbred Canine/dog 42
Retriever - Labrador 33
Shepherd Dog - German 22
Boxer (German Boxer) 19
Dog (unknown) 17
Shih Tzu 17
Retriever - Golden 16
Domestic (unspecified) 14
Chihuahua 13

Associated Drugs

Carprofen 81
Maropitant Citrate 37
Moxidectin 35
Oclacitinib Maleate 33
Milbemycin Oxime + Spinosad 32
Cefovecin 29
Fluralaner Chew Tablets 28
Bedinvetmab 24
Prednisone 21
Afoxolaner 20
Gabapentin 20
Meloxicam 18
Trilostane 18
Doxycycline 18
Pyrantel Pamoate;Sarolaner 16
Isoflurane 15
Ketamine 15
Dexamethasone 15
Cyclosporine 14
Buprenorphine 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Oral bleeding, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (566 here).

Similar death-coded share

Nearest other reactions by death-coded share (44.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Oral bleeding (#596 of 2,481 by report volume); death-coded 44.3%. PlainBreed reaction plate · death-coded report count stamp 251 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →