Reaction profile

The FDA adverse-event record for haemolytic anaemia

139 FDA adverse-event reports reference haemolytic anaemia (VeDDRA 147). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1227 of 2,481
by report volume (all reactions)
139
reports citing this reaction
36.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Haemolytic anaemia has 139 reports now versus 138 in that prior snapshot: 1 more (0.7%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Haemolytic anaemia changes

FDA AER · VeDDRA plate

Code 147 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 139 reports
  • DEATH-HOT 36.7%
  • MID-PACK #1227/2481
  • PHOTO-FINISH INEFFECTIVE, ESTRUS S…
  • SPECIES-DOG Dog · 106
  • DRUG-LEAD Milbemycin Oxime… · 22
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: INEFFECTIVE, ESTRUS SUPPRESSIO (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Haemolytic anaemia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Dehiscence, medical d… · near140Haemolytic anaemia · this re…139INEFFECTIVE, ESTRUS S… · near139Injection site serous… · near139Ventricular arrhythmia · near139Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Haemolytic anaemia

Haemolytic anaemia: high death-coded share in the FDA AER plate

Signature read: Haemolytic anaemia's 36.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 51 of 139 reports (36.7% of named reports). Nearest volume peer: INEFFECTIVE, ESTRUS SUPPRESSIO (±0 reports). Lead species Dog (106). Lead co-reported drug Milbemycin Oxime + Spinosad (22).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 106
Cat 28
Horse 3
Cockatiel 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 16
Crossbred Canine/dog 7
Shih Tzu 7
Retriever - Labrador 6
Dog (unknown) 6
Chihuahua 5
Shepherd Dog - German 5
Schnauzer (unspecified) 4
Dachshund - Miniature 4
Schnauzer - Miniature 4

Associated Drugs

Milbemycin Oxime + Spinosad 22
Cefovecin 17
Enrofloxacin 8
Oclacitinib Maleate 8
Prednisone 7
Carprofen 7
Dexamethasone 6
Afoxolaner 6
Famotidine 5
Prednisolone 5
Moxidectin 5
Fluralaner Chew Tablets 5
Dexmedetomidine Hydrochloride 4
Imidacloprid + Moxidectin 4
Buprenorphine 4
Doxycycline 4
Meloxicam 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Fipronil 10%/S Methoprene 9% Spot On 3
Propofol 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Haemolytic anaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (36.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Haemolytic anaemia (#1227 of 2,481 by report volume); death-coded 36.7%. PlainBreed reaction plate · death-coded share stamp 36.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →