Reaction profile

The FDA adverse-event record for vials, leaking

2,887 FDA reports name vials, leaking, a high-volume reaction in the CVM extract (VeDDRA 99035). Plate stamps and neighbourhood peers follow.

#163 of 2,481
by report volume (all reactions)
2,887
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vials, Leaking has 2,887 reports now versus 2,878 in that prior snapshot: 9 more (0.3%).

Report change
+9
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vials, Leaking changes

FDA AER · VeDDRA plate

Code 99035 VOL-MID

VOL-MID · DEATH-RARE · TOP-DECILE · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,887 reports
  • DEATH-RARE 0.0%
  • TOP-DECILE #163/2481
  • PHOTO-FINISH Skin scab
  • SPECIES-UNKNOWN Unknown · 2,840
  • DRUG-LEAD Meloxicam · 1,328
  • DESK-WIDE 9 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Skin scab (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Vials, Leaking

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Drug dose administrat… · near2892Skin scab · near2891Vials, Leaking · this reacti…2887Unclassifiable advers… · near2876Neurological signs NOS · near2859Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vials, Leaking

Vials, Leaking: low death-coded share in the FDA AER plate

Signature read: 2,887 reports place Vials, Leaking in the upper third of FDA AER volume (#163 of 2,481). Report volume is upper-third scale: 2,887 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 2,887 reports (0.0% of named reports). Nearest volume peer: Skin scab (±4 reports). Lead species Unknown (2,840). Lead co-reported drug Meloxicam (1,328).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Meloxicam appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 2,840
Human 38
Dog 5
Cat 2
Cattle 1
Horse 1

Breeds Most Affected

Unknown 2,879
Cattle (unknown) 1
Quarter Horse 1
Mountain Dog - Bernese 1
Retriever - Labrador 1
Dog (unknown) 1
Terrier - Jack Russell 1
Domestic Mediumhair 1
Siamese 1

Associated Drugs

Meloxicam 1,328
Moxidectin 143
Doramectin 105
Cyclosporine 101
Fluralaner Spot-On Solution 92
Insulin Injectable Vial 82
Enrofloxacin 56
Copper Naphthenate 49
Dirlotapide 49
Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride 43
Ivermectin 40
Protamine Zinc Recombinant Human Insulin 33
Eprinomectin 28
Melarsomine Dihydrochloride Injection 27
Fenbendazole 26
Polysulfated Glycosaminoglycan 23
Orbifloxacin 21
Atipamezole Hydrochloride 21
Amitraz 20
Orbifloxacin Oral Suspension 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Vials, Leaking, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vials, Leaking (#163 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · report volume stamp 2,887 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →