Reddening of the skin
VeDDRA Code: 946
3,939 adverse event reports referencing this reaction
3,939
Total Reports
90
Deaths
230.0%
Death Rate
Species Most Affected
Dog 3,447
Cat 344
Human 113
Horse 11
Cattle 9
Pig 7
Wolf 3
Other Canids 2
Unknown 1
Hamster 1
Breeds Most Affected
Retriever - Labrador 248
Crossbred Canine/dog 221
Domestic Shorthair 218
Chihuahua 194
Terrier - Yorkshire 167
Shih Tzu 137
Terrier - Bull - American Pit 133
Unknown 120
Pit Bull 119
Shepherd Dog - German 105
Associated Drugs
Milbemycin Oxime + Spinosad 762
Moxidectin 437
Afoxolaner 303
Spinosad 244
Oclacitinib Maleate 219
Pyrantel Pamoate;Sarolaner 139
Fluralaner Chew Tablets 118
Ivermectin + Pyrantel As Pamoate Salt 114
Selamectin 112
Anti-Il31 Mab Mcs Lot #1283563 106
Nitenpyram 105
Carprofen 97
Milbemycin Oxime + Praziquantel 96
Prednisone 93
Sarolaner 92
Fluralaner 13.64% 12-Week Chew 91
Maropitant Citrate 87
Cefovecin 84
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 82
Frunevetmab 77
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.