Fluid from nose

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VeDDRA Code: 2482

67 adverse event reports referencing this reaction

67
Total Reports
29
Deaths
4330.0%
Death Rate

Species Most Affected

Dog 51
Cat 13
Cattle 2
Horse 1

Breeds Most Affected

Retriever - Golden 5
Domestic Shorthair 4
Retriever - Labrador 4
Domestic Mediumhair 4
Pit Bull 4
Chihuahua 3
Shepherd Dog - German 3
Crossbred Canine/dog 3
Maine Coon 3
Shih Tzu 2

Associated Drugs

Maropitant Citrate 8
Afoxolaner 6
Carprofen 5
Oclacitinib Maleate 5
Milbemycin Oxime + Praziquantel 5
Ketamine 4
Ivermectin + Pyrantel As Pamoate Salt 4
Butorphanol 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Cefovecin 3
Dexmedetomidine Hydrochloride 3
Buprenorphine 3
Anti-Il31 Mab Mcs Lot #1283563 3
Imidacloprid + Moxidectin 3
Furosemide 3
Fluralaner Chew Tablets 3
Polysulfated Glycosaminoglycan 3
Fluralaner 13.64% 12-Week Chew 3
Atipamezole Hydrochloride 2
Sam-E, Silybin, Vitamin E, Zinc 2

Data Summary

Metric Value
Total reports referencing reaction 67
Reports with fatal outcome 29
Case-fatality rate (reported events) 4330.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2482.

Fluid from nose Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 67 adverse event reports that reference Fluid from nose as a reaction term, including 29 reports with a death outcome — a 4330.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2482, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Fluid from nose appears most frequently in reports for Dog (51 reports), Cat (13 reports), Cattle (2 reports) — with Dog dominating at 51 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Golden (5), Domestic Shorthair (4), Retriever - Labrador (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Fluid from nose are Maropitant Citrate (8 reports), Afoxolaner (6 reports), Carprofen (5 reports), Oclacitinib Maleate (5 reports), with Maropitant Citrate appearing alongside this reaction in 8 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial