Reaction profile

The FDA adverse-event record for flaccid muscles

40 FDA adverse-event reports reference flaccid muscles (VeDDRA 2250). See the species, breeds, and drugs most associated with it below.

40
reports citing this reaction
30.0%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
40
Total Reports
12
Deaths
30.0%
Death Rate

Species Most Affected

Dog 31
Cat 8
Goat 1

Breeds Most Affected

Domestic Shorthair 6
Crossbred Canine/dog 4
Terrier - Bull - American Pit 3
Pug 3
Collie - Border 2
Chihuahua 2
Poodle - Miniature 2
Shih Tzu 2
Terrier - Bull - Staffordshire 1
Nubian 1

Associated Drugs

Oclacitinib Maleate 5
Maropitant Citrate 4
Bedinvetmab 4
Selamectin 3
Pyrantel Pamoate;Sarolaner 3
Frunevetmab 3
Melarsomine Dihydrochloride Injection 2
Milbemycin Oxime + Spinosad 2
Fluralaner Chew Tablets 2
Miconazole 2
Moxidectin 2
Dexamethasone 2
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Ketoconazole,Hydrocortisone 2
Meclizine 2
Eye Lube 2
Fluid Therapy (Unknown) 2
Pilocarpine 2
Imidacloprid + Moxidectin 2
Chlorhexidine Digluconate 2

Flaccid muscles Reaction Insights

40 reports name Flaccid muscles; 12 recorded a death outcome (30.0% of reported events, not a population-level mortality rate). VeDDRA code: 2250.

By species: Dog (31 reports), Cat (8 reports), Goat (1 reports). By breed: Domestic Shorthair (6), Crossbred Canine/dog (4), Terrier - Bull - American Pit (3).

Most co-reported drugs: Oclacitinib Maleate (5 reports), Maropitant Citrate (4 reports), Bedinvetmab (4 reports), Selamectin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.