Hind limb paresis

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VeDDRA Code: 1153

2,023 adverse event reports referencing this reaction

2,023
Total Reports
482
Deaths
2380.0%
Death Rate

Species Most Affected

Dog 1,735
Cat 244
Horse 18
Cattle 13
Pig 3
Other 2
Donkey 2
Other Birds 1
Chicken 1
Turkey 1

Breeds Most Affected

Retriever - Labrador 218
Crossbred Canine/dog 149
Shepherd Dog - German 122
Domestic Shorthair 116
Retriever - Golden 94
Dog (unknown) 63
Domestic (unspecified) 52
Shih Tzu 46
Chihuahua 41
Beagle 40

Associated Drugs

Bedinvetmab 585
Carprofen 278
Gabapentin 214
Moxidectin 100
Trilostane 94
Milbemycin Oxime + Spinosad 92
Afoxolaner 89
Maropitant Citrate 73
Prednisone 67
Frunevetmab 65
Ivermectin + Pyrantel As Pamoate Salt 53
Cefovecin 49
Oclacitinib Maleate 49
Sarolaner 48
Spinosad 47
Meloxicam 44
Selamectin 43
Melarsomine Dihydrochloride 43
Pyrantel Pamoate;Sarolaner 42
Firocoxib 39

Data Summary

Metric Value
Total reports referencing reaction 2,023
Reports with fatal outcome 482
Case-fatality rate (reported events) 2380.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1153.

Hind limb paresis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,023 adverse event reports that reference Hind limb paresis as a reaction term, including 482 reports with a death outcome — a 2380.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1153, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hind limb paresis appears most frequently in reports for Dog (1,735 reports), Cat (244 reports), Horse (18 reports) — with Dog dominating at 1,735 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (218), Crossbred Canine/dog (149), Shepherd Dog - German (122). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hind limb paresis are Bedinvetmab (585 reports), Carprofen (278 reports), Gabapentin (214 reports), Moxidectin (100 reports), with Bedinvetmab appearing alongside this reaction in 585 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial