Reaction profile

The FDA adverse-event record for hind limb paresis

2,118 FDA reports name hind limb paresis, a high-volume reaction in the CVM extract (VeDDRA 1153). Plate stamps and neighbourhood peers follow.

#221 of 2,481
by report volume (all reactions)
2,118
reports citing this reaction
24.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hind limb paresis has 2,118 reports now versus 2,076 in that prior snapshot: 42 more (2.0%).

Report change
+42
Death-coded reports
+12
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hind limb paresis changes

FDA AER · VeDDRA plate

Code 1153 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,118 reports
  • DEATH-HOT 24.3%
  • TOP-DECILE #221/2481
  • PHOTO-FINISH Application site redd…
  • SPECIES-DOG Dog · 1,810
  • DRUG-LEAD Bedinvetmab · 645
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site reddening (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hind limb paresis

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Elevated amylase · near2124Retching · near2121Application site redd… · near2120Hind limb paresis · this rea…2118General illness · near2106Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hind limb paresis

Hind limb paresis: high death-coded share in the FDA AER plate

Signature read: 515 death-coded reports is a heavy tail count for Hind limb paresis in the CVM extract. Report volume is upper-third scale: 2,118 named reports in the openFDA extract. Death-coded share is upper-third: 515 of 2,118 reports (24.3% of named reports). Nearest volume peer: Application site reddening (±2 reports). Lead species Dog (1,810). Lead co-reported drug Bedinvetmab (645).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,810
Cat 263
Horse 19
Cattle 13
Pig 3
Other 2
Donkey 2
Other Birds 1
Chicken 1
Turkey 1

Breeds Most Affected

Retriever - Labrador 228
Crossbred Canine/dog 149
Domestic Shorthair 128
Shepherd Dog - German 127
Retriever - Golden 100
Dog (unknown) 64
Domestic (unspecified) 52
Shih Tzu 47
Chihuahua 43
Beagle 41

Associated Drugs

Bedinvetmab 645
Carprofen 287
Gabapentin 231
Moxidectin 101
Trilostane 95
Afoxolaner 93
Milbemycin Oxime + Spinosad 92
Frunevetmab 78
Maropitant Citrate 75
Prednisone 71
Oclacitinib Maleate 55
Ivermectin + Pyrantel As Pamoate Salt 54
Cefovecin 49
Sarolaner 48
Spinosad 47
Pyrantel Pamoate;Sarolaner 47
Meloxicam 45
Selamectin 44
Melarsomine Dihydrochloride 44
Grapiprant 41

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hind limb paresis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,118 here).

Similar death-coded share

Nearest other reactions by death-coded share (24.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hind limb paresis (#221 of 2,481 by report volume); death-coded 24.3%. PlainBreed reaction plate · death-coded report count stamp 515 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →