Wound

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VeDDRA Code: 2593

945 adverse event reports referencing this reaction

945
Total Reports
83
Deaths
880.0%
Death Rate

Species Most Affected

Dog 689
Cat 223
Human 18
Horse 6
Cattle 3
Pig 2
Other Rodents 1
Other 1
Unknown 1
Chicken 1

Breeds Most Affected

Domestic Shorthair 140
Retriever - Labrador 74
Dog (unknown) 61
Boxer (German Boxer) 55
Pit Bull 54
Retriever - Golden 33
Crossbred Canine/dog 30
Shepherd Dog - German 28
Beagle 23
Domestic Longhair 22

Associated Drugs

Tigilanol Tiglate 374
Frunevetmab 104
Gabapentin 86
Diphenhydramine 81
Prednisone 70
Famotidine 64
Maropitant Citrate 61
Butorphanol 60
Dexmedetomidine 54
Carprofen 40
Milbemycin Oxime + Praziquantel 39
Oclacitinib Maleate 35
Propofol 35
Atipamezole 33
Cefovecin 33
Buprenorphine 33
Bedinvetmab 33
Milbemycin Oxime + Spinosad 28
Isoflurane 27
Butorphanol Tartrate 26

Data Summary

Metric Value
Total reports referencing reaction 945
Reports with fatal outcome 83
Case-fatality rate (reported events) 880.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2593.

Wound Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 945 adverse event reports that reference Wound as a reaction term, including 83 reports with a death outcome — a 880.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2593, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Wound appears most frequently in reports for Dog (689 reports), Cat (223 reports), Human (18 reports) — with Dog dominating at 689 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (140), Retriever - Labrador (74), Dog (unknown) (61). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Wound are Tigilanol Tiglate (374 reports), Frunevetmab (104 reports), Gabapentin (86 reports), Diphenhydramine (81 reports), with Tigilanol Tiglate appearing alongside this reaction in 374 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial