Reaction profile

The FDA adverse-event record for wound

945 FDA adverse-event reports reference wound (VeDDRA 2593). See the species, breeds, and drugs most associated with it below.

945
reports citing this reaction
8.8%
death-coded share
Dog
most-affected species
Tigilanol Tiglate
most-associated drug
Verify with FDA CVM →
945
Total Reports
83
Deaths
8.8%
Death Rate

Species Most Affected

Dog 689
Cat 223
Human 18
Horse 6
Cattle 3
Pig 2
Other Rodents 1
Other 1
Unknown 1
Chicken 1

Breeds Most Affected

Domestic Shorthair 140
Retriever - Labrador 74
Dog (unknown) 61
Boxer (German Boxer) 55
Pit Bull 54
Retriever - Golden 33
Crossbred Canine/dog 30
Shepherd Dog - German 28
Beagle 23
Domestic Longhair 22

Associated Drugs

Tigilanol Tiglate 374
Frunevetmab 104
Gabapentin 86
Diphenhydramine 81
Prednisone 70
Famotidine 64
Maropitant Citrate 61
Butorphanol 60
Dexmedetomidine 54
Carprofen 40
Milbemycin Oxime + Praziquantel 39
Oclacitinib Maleate 35
Propofol 35
Atipamezole 33
Cefovecin 33
Buprenorphine 33
Bedinvetmab 33
Milbemycin Oxime + Spinosad 28
Isoflurane 27
Butorphanol Tartrate 26

Wound Reaction Insights

945 reports name Wound; 83 recorded a death outcome (8.8% of reported events, not a population-level mortality rate). VeDDRA code: 2593.

By species: Dog (689 reports), Cat (223 reports), Human (18 reports). By breed: Domestic Shorthair (140), Retriever - Labrador (74), Dog (unknown) (61).

Most co-reported drugs: Tigilanol Tiglate (374 reports), Frunevetmab (104 reports), Gabapentin (86 reports), Diphenhydramine (81 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.