Reaction profile

The FDA adverse-event record for laryngeal oedema

65 FDA adverse-event reports reference laryngeal oedema (VeDDRA 1574). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1614 of 2,481
by report volume (all reactions)
65
reports citing this reaction
41.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Laryngeal oedema has 65 reports now versus 63 in that prior snapshot: 2 more (3.2%).

Report change
+2
Death-coded reports
+0
Death-coded share
−1.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Laryngeal oedema changes

FDA AER · VeDDRA plate

Code 1574 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 65 reports
  • DEATH-HOT 41.5%
  • MID-PACK #1614/2481
  • PHOTO-FINISH Acne
  • SPECIES-DOG Dog · 43
  • DRUG-LEAD Moxidectin · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acne (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Laryngeal oedema

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acne · near65Gut sounds decreased · near65Hair standing on end · near65Immune-mediated polya… · near65Laryngeal oedema · this reac…65Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Laryngeal oedema

Laryngeal oedema: high death-coded share in the FDA AER plate

Signature read: Laryngeal oedema's 41.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 27 of 65 reports (41.5% of named reports). Nearest volume peer: Acne (±0 reports). Lead species Dog (43). Lead co-reported drug Moxidectin (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 43
Cat 14
Cattle 5
Horse 2
Human 1

Breeds Most Affected

Domestic Shorthair 9
Bulldog 6
Retriever - Golden 4
Spitz - German Pomeranian 3
Chihuahua 3
Crossbred Canine/dog 3
Terrier - Yorkshire 3
Cattle (unknown) 2
Pug 2
Hereford cattle 2

Associated Drugs

Moxidectin 8
Maropitant Citrate 7
Dexamethasone 6
Carprofen 5
Propofol 5
Isoflurane 5
Diphenhydramine Hcl 4
Cefovecin 4
Dexmedetomidine Hydrochloride 4
Epinephrine 3
Butorphanol 3
Buprenorphine 3
Midazolam Hydrochloride 3
Butorphanol Tartrate 3
Selamectin 2
Rabies Virus, Kv 2
Anesthetic 2
Omeprazole 2
Lepto Vaccine 2
Enrofloxacin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Laryngeal oedema, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (65 here).

Similar death-coded share

Nearest other reactions by death-coded share (41.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Laryngeal oedema (#1614 of 2,481 by report volume); death-coded 41.5%. PlainBreed reaction plate · death-coded share stamp 41.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →