Reaction profile

The FDA adverse-event record for laryngeal oedema

61 FDA adverse-event reports reference laryngeal oedema (VeDDRA 1574). See the species, breeds, and drugs most associated with it below.

61
reports citing this reaction
42.6%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
61
Total Reports
26
Deaths
42.6%
Death Rate

Species Most Affected

Dog 41
Cat 13
Cattle 5
Human 1
Horse 1

Breeds Most Affected

Domestic Shorthair 8
Bulldog 6
Retriever - Golden 4
Spitz - German Pomeranian 3
Chihuahua 3
Terrier - Yorkshire 3
Cattle (unknown) 2
Crossbred Canine/dog 2
Pug 2
Hereford cattle 2

Associated Drugs

Moxidectin 8
Dexamethasone 6
Maropitant Citrate 6
Carprofen 5
Propofol 5
Diphenhydramine Hcl 4
Isoflurane 4
Cefovecin 4
Dexmedetomidine Hydrochloride 4
Epinephrine 3
Butorphanol 3
Buprenorphine 3
Midazolam Hydrochloride 3
Butorphanol Tartrate 3
Selamectin 2
Rabies Virus, Kv 2
Anesthetic 2
Omeprazole 2
Lepto Vaccine 2
Enrofloxacin 2

Laryngeal oedema Reaction Insights

61 reports name Laryngeal oedema; 26 recorded a death outcome (42.6% of reported events, not a population-level mortality rate). VeDDRA code: 1574.

By species: Dog (41 reports), Cat (13 reports), Cattle (5 reports). By breed: Domestic Shorthair (8), Bulldog (6), Retriever - Golden (4).

Most co-reported drugs: Moxidectin (8 reports), Dexamethasone (6 reports), Maropitant Citrate (6 reports), Carprofen (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.