Reaction profile

The FDA adverse-event record for increased appetite

770 FDA adverse-event reports reference increased appetite (VeDDRA 1530). See the species, breeds, and drugs most associated with it below.

770
reports citing this reaction
6.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
770
Total Reports
51
Deaths
6.6%
Death Rate

Species Most Affected

Dog 530
Cat 223
Cattle 9
Horse 4
Ferret 1
Wolf 1
Human 1
Turkey 1

Breeds Most Affected

Domestic Shorthair 135
Retriever - Labrador 47
Crossbred Canine/dog 34
Chihuahua 29
Dog (unknown) 29
Retriever - Golden 27
Cat (unknown) 27
Shepherd Dog - German 20
Boxer (German Boxer) 19
Terrier - Yorkshire 17

Associated Drugs

Oclacitinib Maleate 91
Bexagliflozin 55
Bedinvetmab 53
Milbemycin Oxime + Spinosad 49
Trilostane 43
Spinosad 38
Buprenorphine 34
Prednisone 32
Carprofen 27
Gabapentin 27
Frunevetmab 26
Insulin Injectable Vial 24
Afoxolaner 23
Maropitant Citrate 22
Imepitoin 19
Ivermectin + Pyrantel As Pamoate Salt 18
Milbemycin Oxime + Praziquantel 18
Praziquantel 18
Grapiprant 16
Imidacloprid + Moxidectin 15

Increased appetite Reaction Insights

770 reports name Increased appetite; 51 recorded a death outcome (6.6% of reported events, not a population-level mortality rate). VeDDRA code: 1530.

By species: Dog (530 reports), Cat (223 reports), Cattle (9 reports). By breed: Domestic Shorthair (135), Retriever - Labrador (47), Crossbred Canine/dog (34).

Most co-reported drugs: Oclacitinib Maleate (91 reports), Bexagliflozin (55 reports), Bedinvetmab (53 reports), Milbemycin Oxime + Spinosad (49 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.