Reaction profile

The FDA adverse-event record for increased appetite

825 FDA reports name increased appetite, a high-volume reaction in the CVM extract (VeDDRA 1530). Plate stamps and neighbourhood peers follow.

#453 of 2,481
by report volume (all reactions)
825
reports citing this reaction
6.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased appetite has 825 reports now versus 802 in that prior snapshot: 23 more (2.9%).

Report change
+23
Death-coded reports
+3
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased appetite changes

FDA AER · VeDDRA plate

Code 1530 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 825 reports
  • DEATH-PAR 6.8%
  • UPPER-Q #453/2481
  • PHOTO-FINISH Abdominal discomfort
  • SPECIES-DOG Dog · 562
  • DRUG-LEAD Oclacitinib Malea… · 95
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal discomfort (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Increased appetite

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hepatomegaly · near827Squinting · near826Abdominal discomfort · near825Increased appetite · this re…825Decreased bowel movem… · near821Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased appetite

Increased appetite: low death-coded share in the FDA AER plate

Signature read: 825 reports place Increased appetite in the upper third of FDA AER volume (#453 of 2,481). Report volume is upper-third scale: 825 named reports in the openFDA extract. Death-coded share is lower-third: 56 of 825 reports (6.8% of named reports). Nearest volume peer: Abdominal discomfort (±0 reports). Lead species Dog (562). Lead co-reported drug Oclacitinib Maleate (95).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 562
Cat 244
Cattle 10
Horse 4
Human 2
Ferret 1
Wolf 1
Turkey 1

Breeds Most Affected

Domestic Shorthair 145
Retriever - Labrador 48
Crossbred Canine/dog 35
Chihuahua 29
Dog (unknown) 29
Retriever - Golden 29
Cat (unknown) 28
Shepherd Dog - German 22
Boxer (German Boxer) 21
Terrier - Yorkshire 17

Associated Drugs

Oclacitinib Maleate 95
Bexagliflozin 64
Bedinvetmab 60
Trilostane 59
Milbemycin Oxime + Spinosad 49
Buprenorphine 41
Spinosad 38
Gabapentin 35
Prednisone 33
Carprofen 29
Frunevetmab 26
Maropitant Citrate 25
Insulin Injectable Vial 25
Afoxolaner 23
Ivermectin + Pyrantel As Pamoate Salt 19
Milbemycin Oxime + Praziquantel 19
Imepitoin 19
Praziquantel 18
Grapiprant 17
Anti-Il31 Mab Mcs Lot #1283563 16

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased appetite, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (825 here).

Similar death-coded share

Nearest other reactions by death-coded share (6.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased appetite (#453 of 2,481 by report volume); death-coded 6.8%. PlainBreed reaction plate · report volume stamp 825 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →