Not sleeping
VeDDRA Code: 140
1,136 adverse event reports referencing this reaction
1,136
Total Reports
77
Deaths
680.0%
Death Rate
Species Most Affected
Dog 726
Cat 408
Horse 1
Unknown 1
Breeds Most Affected
Domestic Shorthair 217
Cat (unknown) 70
Retriever - Labrador 58
Crossbred Canine/dog 53
Shih Tzu 36
Maltese 32
Terrier - Yorkshire 30
Retriever - Golden 30
Chihuahua 29
Dog (unknown) 27
Associated Drugs
Buprenorphine 361
Milbemycin Oxime + Spinosad 100
Isoflurane 78
Maropitant Citrate 71
Robenacoxib 70
Gabapentin 57
Afoxolaner 56
Dexmedetomidine 55
Propofol 48
Ketamine 46
Carprofen 45
Cefovecin Sodium 45
Trilostane 44
Butorphanol 44
Ivermectin + Pyrantel As Pamoate Salt 41
Pyrantel Pamoate;Sarolaner 41
Midazolam 39
Spinosad 37
Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On 37
Bedinvetmab 37
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.