Reaction profile

The FDA adverse-event record for azotaemia

1,466 FDA adverse-event reports reference azotaemia (VeDDRA 2182). See the species, breeds, and drugs most associated with it below.

1,466
reports citing this reaction
35.6%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
1,466
Total Reports
522
Deaths
35.6%
Death Rate

Species Most Affected

Dog 1,058
Cat 393
Horse 11
Sheep 1
Human 1
Cougar 1
Monkey 1

Breeds Most Affected

Domestic Shorthair 191
Retriever - Labrador 155
Crossbred Canine/dog 76
Domestic (unspecified) 70
Retriever - Golden 51
Chihuahua 45
Terrier - Yorkshire 37
Shepherd Dog - German 37
Collie - Border 30
Boxer (German Boxer) 29

Associated Drugs

Carprofen 208
Maropitant Citrate 187
Meloxicam 180
Bedinvetmab 124
Oclacitinib Maleate 114
Deracoxib 98
Gabapentin 90
Grapiprant 81
Trilostane 66
Tramadol 54
Buprenorphine 50
Isoflurane 45
Cefovecin 45
Famotidine 41
Frunevetmab 41
Moxidectin 40
Milbemycin Oxime + Spinosad 39
Prednisone 38
Robenacoxib 38
Bexagliflozin 34

Azotaemia Reaction Insights

1,466 reports name Azotaemia; 522 recorded a death outcome (35.6% of reported events, not a population-level mortality rate). VeDDRA code: 2182.

By species: Dog (1,058 reports), Cat (393 reports), Horse (11 reports). By breed: Domestic Shorthair (191), Retriever - Labrador (155), Crossbred Canine/dog (76).

Most co-reported drugs: Carprofen (208 reports), Maropitant Citrate (187 reports), Meloxicam (180 reports), Bedinvetmab (124 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.