Reaction profile

The FDA adverse-event record for azotaemia

1,557 FDA reports name azotaemia, a high-volume reaction in the CVM extract (VeDDRA 2182). Plate stamps and neighbourhood peers follow.

#275 of 2,481
by report volume (all reactions)
1,557
reports citing this reaction
35.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Azotaemia has 1,557 reports now versus 1,516 in that prior snapshot: 41 more (2.7%).

Report change
+41
Death-coded reports
+11
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Azotaemia changes

FDA AER · VeDDRA plate

Code 2182 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,557 reports
  • DEATH-HOT 35.6%
  • UPPER-Q #275/2481
  • PHOTO-FINISH Hyperthermia
  • SPECIES-DOG Dog · 1,110
  • DRUG-LEAD Carprofen · 219
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperthermia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Azotaemia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Azotaemia · this reaction1557Hyperthermia · near1557Generalised itching · near1555Arthritis · near1535Increased respiratory… · near1534Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Azotaemia

Azotaemia: high death-coded share in the FDA AER plate

Signature read: 555 death-coded reports is a heavy tail count for Azotaemia in the CVM extract. Report volume is upper-third scale: 1,557 named reports in the openFDA extract. Death-coded share is upper-third: 555 of 1,557 reports (35.6% of named reports). Nearest volume peer: Hyperthermia (±0 reports). Lead species Dog (1,110). Lead co-reported drug Carprofen (219).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,110
Cat 429
Horse 14
Sheep 1
Human 1
Cougar 1
Monkey 1

Breeds Most Affected

Domestic Shorthair 215
Retriever - Labrador 161
Crossbred Canine/dog 79
Domestic (unspecified) 70
Retriever - Golden 55
Chihuahua 46
Terrier - Yorkshire 40
Shepherd Dog - German 37
Boxer (German Boxer) 31
Collie - Border 31

Associated Drugs

Carprofen 219
Maropitant Citrate 204
Meloxicam 184
Bedinvetmab 137
Oclacitinib Maleate 124
Gabapentin 104
Deracoxib 99
Grapiprant 83
Trilostane 67
Buprenorphine 60
Tramadol 54
Frunevetmab 52
Isoflurane 49
Cefovecin 46
Famotidine 45
Moxidectin 43
Robenacoxib 43
Bexagliflozin 43
Enrofloxacin 39
Milbemycin Oxime + Spinosad 39

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Azotaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,557 here).

Similar death-coded share

Nearest other reactions by death-coded share (35.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Azotaemia (#275 of 2,481 by report volume); death-coded 35.6%. PlainBreed reaction plate · death-coded report count stamp 555 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →