Excoriation

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VeDDRA Code: 1198

511 adverse event reports referencing this reaction

511
Total Reports
21
Deaths
410.0%
Death Rate

Species Most Affected

Cat 268
Dog 231
Horse 6
Cattle 3
Rabbit 2
Bat 1

Breeds Most Affected

Domestic Shorthair 186
Retriever - Labrador 33
Domestic Longhair 25
Crossbred Canine/dog 19
Domestic Mediumhair 12
Terrier - Yorkshire 12
Cat (unknown) 10
Siamese 10
Pit Bull 10
Chihuahua 10

Associated Drugs

Frunevetmab 117
Selamectin 44
Cefovecin 38
Thiamazole 35
Afoxolaner 31
Fluralaner Chew Tablets 24
Imidacloprid + Moxidectin 22
Milbemycin Oxime + Spinosad 22
Maropitant Citrate 17
Gabapentin 17
Oclacitinib Maleate 14
Carprofen 12
Fluralaner Spot-On Solution 12
Methimazole 11
Moxidectin 11
Cyclosporine 10
Diphenhydramine 10
Trilostane 10
Methylprednisolone Acetate 10
Rabacfosadine Succinate 10

Data Summary

Metric Value
Total reports referencing reaction 511
Reports with fatal outcome 21
Case-fatality rate (reported events) 410.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1198.

Excoriation Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 511 adverse event reports that reference Excoriation as a reaction term, including 21 reports with a death outcome — a 410.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1198, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Excoriation appears most frequently in reports for Cat (268 reports), Dog (231 reports), Horse (6 reports) — with Cat dominating at 268 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (186), Retriever - Labrador (33), Domestic Longhair (25). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Excoriation are Frunevetmab (117 reports), Selamectin (44 reports), Cefovecin (38 reports), Thiamazole (35 reports), with Frunevetmab appearing alongside this reaction in 117 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial