Reaction profile

The FDA adverse-event record for lymphadenitis

50 FDA reports name lymphadenitis, a lower-volume reaction in the CVM extract (VeDDRA 173). Plate stamps and neighbourhood peers follow.

#1738 of 2,481
by report volume (all reactions)
50
reports citing this reaction
28.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lymphadenitis has 50 reports now versus 48 in that prior snapshot: 2 more (4.2%).

Report change
+2
Death-coded reports
+0
Death-coded share
−1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lymphadenitis changes

FDA AER · VeDDRA plate

Code 173 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 50 reports
  • DEATH-HOT 28.0%
  • MID-PACK #1738/2481
  • PHOTO-FINISH Application site papu…
  • SPECIES-DOG Dog · 40
  • DRUG-LEAD Milbemycin Oxime… · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site papule (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lymphadenitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site papu… · near50Bounding pulse · near50Device-related infect… · near50Eyeball protrusion · near50Lymphadenitis · this reaction50Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lymphadenitis

Lymphadenitis: high death-coded share in the FDA AER plate

Signature read: Lymphadenitis's 28.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 50 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 50 reports (28.0% of named reports). Nearest volume peer: Application site papule (±0 reports). Lead species Dog (40). Lead co-reported drug Milbemycin Oxime + Spinosad (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 40
Cat 8
Human 1
Hedgehog 1

Breeds Most Affected

Domestic Shorthair 6
Dog (other) 3
Mixed (Dog) 2
Dog (unknown) 2
Boxer (German Boxer) 2
Crossbred Canine/dog 2
Retriever - Labrador 2
Ridgeback - Rhodesian 2
Unknown 1
Dachshund (unspecified) 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Carprofen 6
Oclacitinib Maleate 6
Imidacloprid + Moxidectin 5
Prednisone 4
Trilostane 4
Cyclosporine A 4
Maropitant Citrate 4
Spinosad 3
Anesthetic 3
Tramadol 3
Doxycycline 3
Cefpodoxime 3
Ivermectin 2
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 2
Cefovecin 2
Praziquantel 2
Isoflurane 2
Enrofloxacin 2
Meloxicam 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lymphadenitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (50 here).

Similar death-coded share

Nearest other reactions by death-coded share (28.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lymphadenitis (#1738 of 2,481 by report volume); death-coded 28.0%. PlainBreed reaction plate · death-coded share stamp 28.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →