Lack of efficacy (virus) - bovine viral diarrhoea virus

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VeDDRA Code: 2812

22 adverse event reports referencing this reaction

22
Total Reports
19
Deaths
8640.0%
Death Rate

Species Most Affected

Cattle 22

Breeds Most Affected

Mixed (Cattle) 9
Cattle (other) 7
Cattle (unknown) 3
Aberdeen Angus 2
Salers 1

Associated Drugs

Tulathromycin 9
Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 6
Gamithromycin 6
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 4
Bovine Viral Diarrhea Virus, Type 1, Strain Nadl-Sbvd, Msvx+1;Bovine Viral Diarr 4
Ceftiofur Crystalline Free Acid 3
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 2
Fenbendazol Suspension 2
Clos P*2/Cl Oth*4/H.Somnus Kb 2
Moxidectin 2
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 2
Mannheimia Haemolytica, Strain Nl-1009 2
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus 2
Eprinomectin 2
Mannheimia Haemolytica Toxoid 2
Haemophilus Somnus, 10555;Haemophilus Somnus, 8025 2
Oxfendazole 2
Mycoplasma Bovis 2
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 1

Data Summary

Metric Value
Total reports referencing reaction 22
Reports with fatal outcome 19
Case-fatality rate (reported events) 8640.0%
Species observed 1
Breeds observed 5
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2812.

Lack of efficacy (virus) - bovine viral diarrhoea virus Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 22 adverse event reports that reference Lack of efficacy (virus) - bovine viral diarrhoea virus as a reaction term, including 19 reports with a death outcome — a 8640.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2812, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Lack of efficacy (virus) - bovine viral diarrhoea virus appears most frequently in reports for Cattle (22 reports) — with Cattle dominating at 22 entries. Within those species, the breeds most often named alongside this reaction are Mixed (Cattle) (9), Cattle (other) (7), Cattle (unknown) (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Lack of efficacy (virus) - bovine viral diarrhoea virus are Tulathromycin (9 reports), Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (6 reports), Gamithromycin (6 reports), Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid (4 reports), with Tulathromycin appearing alongside this reaction in 9 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial