Reaction profile

The FDA adverse-event record for red blood cells(rbc) nucleated

88 FDA adverse-event reports reference red blood cells(rbc) nucleated (VeDDRA 99336). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1456 of 2,481
by report volume (all reactions)
88
reports citing this reaction
28.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. RED BLOOD CELLS(RBC) NUCLEATED has 88 reports now versus 88 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to RED BLOOD CELLS(RBC) NUCLEATED changes

FDA AER · VeDDRA plate

Code 99336 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 88 reports
  • DEATH-HOT 28.4%
  • MID-PACK #1456/2481
  • PHOTO-FINISH Difficulty in micturi…
  • SPECIES-DOG Dog · 80
  • DRUG-LEAD Carprofen · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Difficulty in micturition (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around RED BLOOD CELLS NUCLEATED

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Difficulty in micturi… · near88Excessive sweating · near88Necrosis NOS · near88RED BLOOD CELLS(RBC)… · this…88Bone marrow disorder… · near87Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around RED BLOOD CELLS(RBC) NUCLEATED

RED BLOOD CELLS(RBC) NUCLEATED: high death-coded share in the FDA AER plate

Signature read: RED BLOOD CELLS(RBC) NUCLEATED's 28.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 25 of 88 reports (28.4% of named reports). Nearest volume peer: Difficulty in micturition (±0 reports). Lead species Dog (80). Lead co-reported drug Carprofen (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 80
Cat 7
Horse 1

Breeds Most Affected

Crossbred Canine/dog 9
Retriever - Labrador 9
Domestic Shorthair 6
Chihuahua 4
Maltese 3
Terrier - West Highland White 3
Spaniel - Cocker American 3
Spitz - German Pomeranian 3
Schnauzer - Miniature 3
Retriever - Golden 3

Associated Drugs

Carprofen 8
Moxidectin 7
Spinosad 6
Prednisone 6
Ivermectin + Pyrantel As Pamoate Salt 6
Cyclosporine 5
Milbemycin Oxime + Spinosad 5
Oclacitinib Maleate 5
Meloxicam 4
Enrofloxacin 4
Grapiprant 4
Pyrantel Pamoate;Sarolaner 4
Deracoxib 3
Trilostane 3
Cyclosporine A 3
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 3
Maropitant Citrate 3
Cefovecin Sodium 2
Glycosaminoglycan Polysulfate 2
Selamectin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for RED BLOOD CELLS(RBC) NUCLEATED, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (88 here).

Similar death-coded share

Nearest other reactions by death-coded share (28.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for RED BLOOD CELLS(RBC) NUCLEATED (#1456 of 2,481 by report volume); death-coded 28.4%. PlainBreed reaction plate · death-coded share stamp 28.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →