Underfilling, Bottles

Verify with FDA CVM →

VeDDRA Code: 99038

1,285 adverse event reports referencing this reaction

1,285
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Unknown 1,277
Cat 4
Dog 2
Human 2

Breeds Most Affected

Unknown 1,279
Domestic Shorthair 2
Cat (unknown) 2
Dog (unknown) 1
Retriever - Golden 1

Associated Drugs

Praziquantel 251
Oclacitinib Maleate 139
Carprofen 99
Pimobendan 67
Genta/Momet/Clotrim Ear Oint 44
Meloxicam 41
Grapiprant 41
Phenylpropanolamine Hcl 37
Fluoxetine 33
Orbiflox/Momet/Posaco Eardrops 30
Imidacloprid 29
Firocoxib 27
Phenylpropropanolamine Hcl 18
Clindamycin Hydrochloride 17
Enrofloxacin 17
Hyaluronic Acid 16
Deracoxib 15
Cyclosporine 15
Firocoxib 57 Mg Chewable 14
Tresaderm Dermatological Solution 13

Data Summary

Metric Value
Total reports referencing reaction 1,285
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 4
Breeds observed 5
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99038.

Underfilling, Bottles Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,285 adverse event reports that reference Underfilling, Bottles as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99038, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Underfilling, Bottles appears most frequently in reports for Unknown (1,277 reports), Cat (4 reports), Dog (2 reports) — with Unknown dominating at 1,277 entries. Within those species, the breeds most often named alongside this reaction are Unknown (1,279), Domestic Shorthair (2), Cat (unknown) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Underfilling, Bottles are Praziquantel (251 reports), Oclacitinib Maleate (139 reports), Carprofen (99 reports), Pimobendan (67 reports), with Praziquantel appearing alongside this reaction in 251 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial