Reaction profile

The FDA adverse-event record for head pressing

348 FDA adverse-event reports reference head pressing (VeDDRA 636). See the species, breeds, and drugs most associated with it below.

348
reports citing this reaction
39.4%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
348
Total Reports
137
Deaths
39.4%
Death Rate

Species Most Affected

Dog 244
Cat 75
Horse 15
Cattle 5
Other Deer 2
Rabbit 2
Guinea Pig 1
Sheep 1
Donkey 1
Human 1

Breeds Most Affected

Domestic Shorthair 38
Crossbred Canine/dog 29
Retriever - Labrador 15
Retriever - Golden 12
Terrier - Yorkshire 11
Shepherd Dog - German 10
Dog (unknown) 9
Chihuahua 7
Terrier - Jack Russell 7
Terrier - Bull - American Pit 7

Associated Drugs

Bedinvetmab 29
Trilostane 27
Carprofen 24
Milbemycin Oxime + Spinosad 24
Maropitant Citrate 22
Afoxolaner 16
Selamectin 13
Spinosad 13
Buprenorphine 13
Cefovecin 13
Fluralaner Chew Tablets 13
Frunevetmab 13
Sarolaner 10
Pyrantel Pamoate;Sarolaner 10
Moxidectin 9
Ivermectin 9
Robenacoxib 9
Famotidine 9
Prednisone 9
Lotilaner 9

Head pressing Reaction Insights

348 reports name Head pressing; 137 recorded a death outcome (39.4% of reported events, not a population-level mortality rate). VeDDRA code: 636.

By species: Dog (244 reports), Cat (75 reports), Horse (15 reports). By breed: Domestic Shorthair (38), Crossbred Canine/dog (29), Retriever - Labrador (15).

Most co-reported drugs: Bedinvetmab (29 reports), Trilostane (27 reports), Carprofen (24 reports), Milbemycin Oxime + Spinosad (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.