Reaction profile

The FDA adverse-event record for uric acid crystals

10 FDA adverse-event reports reference uric acid crystals (VeDDRA 2256). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Meloxicam
most-associated drug
Verify with FDA CVM →
10
Total Reports
1
Deaths
10.0%
Death Rate

Species Most Affected

Dog 8
Cat 2

Breeds Most Affected

Cat (unknown) 2
Bulldog 1
Retriever - Chesapeake Bay 1
Deutsche Dogge, Great Dane 1
Bulldog - American 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Pekingese 1
Boxer (German Boxer) 1
Terrier (unspecified) 1

Associated Drugs

Meloxicam 2
Milbemycin Oxime + Spinosad 2
Oclacitinib Maleate 2
Carprofen 1
Unknown Anesthetics 1
Cefazolin 1
Immunotherapy 1
Chlorhexidine 1
Fluralaner Chew Tablets 1
Milbemycin Oxime + Praziquantel 1
Pradofloxacin 1
Gabapentin 1
Unknown Medication 1
Buprenorphine 1
Fluralaner 13.64% 12-Week Chew 1
Milbemycin/Lufenuron Tablets 1

Uric acid crystals Reaction Insights

10 reports name Uric acid crystals; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 2256.

By species: Dog (8 reports), Cat (2 reports). By breed: Cat (unknown) (2), Bulldog (1), Retriever - Chesapeake Bay (1).

Most co-reported drugs: Meloxicam (2 reports), Milbemycin Oxime + Spinosad (2 reports), Oclacitinib Maleate (2 reports), Carprofen (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.