Reaction profile

The FDA adverse-event record for growling

284 FDA adverse-event reports reference growling (VeDDRA 2755). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#892 of 2,481
by report volume (all reactions)
284
reports citing this reaction
11.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Growling has 284 reports now versus 269 in that prior snapshot: 15 more (5.6%).

Report change
+15
Death-coded reports
+0
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Growling changes

FDA AER · VeDDRA plate

Code 2755 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 284 reports
  • DEATH-ELEV 11.3%
  • MID-PACK #892/2481
  • PHOTO-FINISH Cardiomyopathy
  • SPECIES-DOG Dog · 189
  • DRUG-LEAD Pyrantel Pamoate;… · 38
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiomyopathy (±1 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Growling

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Growling · this reaction284Cardiomyopathy · near283Cognitive disorder NOS · near283Injection site serosa… · near283Lack of efficacy (fun… · near283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Growling

What the FDA AER plate says about Growling

Signature read: report volume at 284 (#892 of 2,481) is the standout scale stamp on Growling. Report volume sits in the middle third of the reaction corpus. 32 of 284 reports were death-coded (11.3% of named reports, not a population mortality rate). Nearest volume peer: Cardiomyopathy (±1 reports). Lead species Dog (189). Lead co-reported drug Pyrantel Pamoate;Sarolaner (38).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pyrantel Pamoate;Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 189
Cat 94
Other 1

Breeds Most Affected

Domestic Shorthair 63
Retriever - Labrador 25
Retriever - Golden 12
Dog (unknown) 12
Crossbred Canine/dog 11
Domestic Mediumhair 9
Domestic Longhair 7
Shepherd Dog - German 7
Terrier - Bull - American Pit 7
Shih Tzu 6

Associated Drugs

Pyrantel Pamoate;Sarolaner 38
Buprenorphine 30
Fluralaner 13.64% 12-Week Chew 18
Gabapentin 17
Oclacitinib Maleate 14
Bedinvetmab 13
Afoxolaner 12
Isoflurane 12
Fluralaner Spot-On Solution 11
Cefovecin 10
Robenacoxib 9
Frunevetmab 9
Lotilaner 8
Rabies Vaccine 8
Maropitant Citrate 8
Ivermectin + Pyrantel As Pamoate Salt 7
Anti-Il31 Mab Mcs Lot #1283563 7
Carprofen 7
Sarolaner 6
Propofol 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Growling, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (11.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Growling (#892 of 2,481 by report volume); death-coded 11.3%. PlainBreed reaction plate · report volume stamp 284 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →