Reaction profile

The FDA adverse-event record for lens luxation

24 FDA adverse-event reports reference lens luxation (VeDDRA 447). See the species, breeds, and drugs most associated with it below.

24
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
24
Total Reports
2
Deaths
8.3%
Death Rate

Species Most Affected

Dog 20
Cat 4

Breeds Most Affected

Chihuahua 4
Terrier (unspecified) 2
Crossbred Canine/dog 2
Domestic Shorthair 2
Terrier - Boston 2
Pug 1
Retriever - Labrador 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Beagle 1
Spaniel - Cocker American 1

Associated Drugs

Oclacitinib Maleate 4
Recombinant Human Insulin 2
Milbemycin Oxime + Spinosad 2
Spinosad 2
Maropitant Citrate 2
Bedinvetmab 2
Diphenhydramine 1
Etofenprox, Piperonyl Butoxide, N-Octyl Bicycloheptene Dicarboximide 1
Fluralaner Chew Tablets 1
Allergy Shot (Unknown) 1
Milbemycin Oxime 1
Imidacloprid; Permethrin; Pyriproxyfen 1
Robenacoxib 1
Orbifloxacin 1
Fluid Therapy (Unknown) 1
Prednisolone; Trimeprazine Tartrate 1
Dorzolamide Hcl 1
Miconazole + Polymyxin B + Prednisolone 1
Ivermectin + Pyrantel Pamoate 1
Insulin Injectable Vial 1

Lens luxation Reaction Insights

24 reports name Lens luxation; 2 recorded a death outcome (8.3% of reported events, not a population-level mortality rate). VeDDRA code: 447.

By species: Dog (20 reports), Cat (4 reports). By breed: Chihuahua (4), Terrier (unspecified) (2), Crossbred Canine/dog (2).

Most co-reported drugs: Oclacitinib Maleate (4 reports), Recombinant Human Insulin (2 reports), Milbemycin Oxime + Spinosad (2 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.