Reaction profile

The FDA adverse-event record for lichenification

78 FDA adverse-event reports reference lichenification (VeDDRA 2037). See the species, breeds, and drugs most associated with it below.

78
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
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78
Total Reports
2
Deaths
2.6%
Death Rate

Species Most Affected

Dog 73
Cat 4
Cattle 1

Breeds Most Affected

Shepherd Dog - German 10
Retriever - Labrador 7
Chihuahua 5
Crossbred Canine/dog 5
Shepherd Dog - Australian 4
Domestic Shorthair 3
Terrier - West Highland White 3
Boxer (German Boxer) 3
Pug 3
Shih Tzu 3

Associated Drugs

Oclacitinib Maleate 23
Anti-Il31 Mab Mcs Lot #1283563 10
Afoxolaner 6
Milbemycin Oxime + Spinosad 5
Maropitant Citrate 5
Cefpodoxime Proxetil 5
Carprofen 4
Tramadol 4
Glucosamine, Chondroitin, Unsaponifiables 4
Cyclosporine 4
Prednisone 4
Fluralaner Chew Tablets 4
Pyrantel Pamoate;Sarolaner 4
Ilunocitinib 4
Imidacloprid + Moxidectin 3
Betamethasone + Florfenicol + Terbinafine 3
Fluralaner 3
Moxidectin 3
Gabapentin 3
Ketoconazole 3

Lichenification Reaction Insights

78 reports name Lichenification; 2 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). VeDDRA code: 2037.

By species: Dog (73 reports), Cat (4 reports), Cattle (1 reports). By breed: Shepherd Dog - German (10), Retriever - Labrador (7), Chihuahua (5).

Most co-reported drugs: Oclacitinib Maleate (23 reports), Anti-Il31 Mab Mcs Lot #1283563 (10 reports), Afoxolaner (6 reports), Milbemycin Oxime + Spinosad (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.