Reaction profile

The FDA adverse-event record for harsh lung sounds

187 FDA adverse-event reports reference harsh lung sounds (VeDDRA 2487). See the species, breeds, and drugs most associated with it below.

187
reports citing this reaction
43.9%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
187
Total Reports
82
Deaths
43.9%
Death Rate

Species Most Affected

Dog 150
Cat 33
Horse 3
Other Canids 1

Breeds Most Affected

Domestic Shorthair 20
Retriever - Labrador 18
Chihuahua 17
Crossbred Canine/dog 9
Retriever - Golden 8
Shepherd Dog - German 7
Maltese 5
Beagle 4
Spitz - German Pomeranian 4
Boxer (German Boxer) 4

Associated Drugs

Maropitant Citrate 35
Melarsomine Dihydrochloride 25
Prednisone 20
Cefovecin 14
Moxidectin 14
Doxycycline 14
Carprofen 14
Gabapentin 13
Bedinvetmab 13
Furosemide 12
Butorphanol 11
Fluralaner Chew Tablets 11
Enrofloxacin 10
Dexamethasone 8
Oclacitinib Maleate 7
Meloxicam 7
Oxygen 7
Anti-Il31 Mab Mcs Lot #1283563 7
Pyrantel Pamoate;Sarolaner 7
Phenobarbital 6

Harsh lung sounds Reaction Insights

187 reports name Harsh lung sounds; 82 recorded a death outcome (43.9% of reported events, not a population-level mortality rate). VeDDRA code: 2487.

By species: Dog (150 reports), Cat (33 reports), Horse (3 reports). By breed: Domestic Shorthair (20), Retriever - Labrador (18), Chihuahua (17).

Most co-reported drugs: Maropitant Citrate (35 reports), Melarsomine Dihydrochloride (25 reports), Prednisone (20 reports), Cefovecin (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.